pycnosis

简明释义

[/pɪkˈnoʊsɪs/][/pɪkˈnoʊsɪs/]

n. [生化] 细胞致密变化;[生化] 固缩(现象)

英英释义

Pycnosis refers to the condensation of chromatin in the nucleus of a cell, leading to the shrinkage of the nucleus and often associated with cell death.

pycnosis指细胞核中染色质的浓缩,导致细胞核的收缩,通常与细胞死亡相关。

单词用法

同义词

pyknosis

细胞浓缩

Pyknosis is often observed during the process of apoptosis.

细胞浓缩通常在细胞凋亡过程中被观察到。

nuclear condensation

核凝缩

Nuclear condensation is a key feature in the diagnosis of certain types of cancer.

核凝缩是某些类型癌症诊断中的一个关键特征。

反义词

karyolysis

核溶解

Karyolysis is often observed in cells undergoing necrosis.

核溶解通常在经历坏死的细胞中观察到。

karyorrhexis

核碎裂

Karyorrhexis indicates severe cell damage and is associated with apoptosis.

核碎裂表示严重的细胞损伤,并与细胞凋亡有关。

例句

1.At postoperative 7 week, the humerus sample showed that osteocyte separated from osseous lacuna, some nucleus pycnosis and rough endoplasmic hollowed;

术后7周实验组肱骨标本可见骨细胞与骨陷窝分离,有的细胞核固缩粗面内质网肿胀空化;

2.At postoperative 7 week, the humerus sample showed that osteocyte separated from osseous lacuna, some nucleus pycnosis and rough endoplasmic hollowed;

术后7周实验组肱骨标本可见骨细胞与骨陷窝分离,有的细胞核固缩粗面内质网肿胀空化;

3.During the examination, the doctor explained that pycnosis 细胞浓缩 is often associated with irreversible cell injury.

在检查过程中,医生解释说pycnosis 细胞浓缩通常与不可逆细胞损伤有关。

4.The researcher observed pycnosis 细胞浓缩 in the cancerous tissue samples, suggesting aggressive tumor behavior.

研究人员在癌性组织样本中观察到了pycnosis 细胞浓缩,这表明肿瘤行为具有侵袭性。

5.In the histopathology report, the pathologist noted that the cells exhibited signs of pycnosis 细胞浓缩, indicating a potential stage of cell death.

在组织病理学报告中,病理学家注意到细胞表现出pycnosis 细胞浓缩的迹象,表明可能处于细胞死亡的阶段。

6.In the context of apoptosis, pycnosis 细胞浓缩 serves as an early indicator of cellular changes.

在凋亡的背景下,pycnosis 细胞浓缩作为细胞变化的早期指示。

7.Histologists often look for pycnosis 细胞浓缩 when assessing tissue damage under a microscope.

组织学家在显微镜下评估组织损伤时,通常会寻找pycnosis 细胞浓缩的迹象。

作文

In the realm of cellular biology, understanding the various changes that cells undergo during different physiological and pathological processes is crucial. One such change is known as pycnosis, which refers to the condensation of chromatin in the nucleus of a cell, leading to a shrunken appearance. This process can often be observed during cellular aging, necrosis, or apoptosis, which is programmed cell death. The significance of pycnosis lies not only in its role as an indicator of cellular distress but also as a fundamental aspect of how cells respond to stressors. To comprehend the implications of pycnosis, it is essential to first understand what chromatin is. Chromatin is a complex of DNA and proteins found in the nucleus of eukaryotic cells. It serves to package DNA into a more compact, dense shape, facilitating the regulation of gene expression and DNA replication. When a cell experiences stress, whether from environmental factors, toxins, or a lack of nutrients, it may initiate a series of responses that ultimately lead to pycnosis. During pycnosis, the chromatin becomes densely packed, and the nucleus shrinks. This morphological change is a hallmark of irreversible cell damage. In many cases, pycnosis is followed by other cellular changes such as karyorrhexis, which is the fragmentation of the nucleus, and karyolysis, the dissolution of the nucleus. These changes are critical in the study of pathology as they can indicate the progression of diseases such as cancer, where cellular regulation is disrupted. Furthermore, pycnosis can serve as a diagnostic marker in histopathological examinations. For instance, when tissue samples are analyzed under a microscope, the presence of pycnosis can suggest that the cells have undergone significant stress or damage, prompting further investigation into the underlying causes. In this way, pycnosis is not merely a cellular phenomenon; it is a reflection of the health of the organism as a whole. In addition to its pathological significance, pycnosis also has implications in developmental biology. During normal embryonic development, controlled cell death is necessary for shaping tissues and organs. In this context, pycnosis plays a role in eliminating unnecessary or damaged cells, thus contributing to the proper formation of the organism. In conclusion, pycnosis is a vital concept in cell biology that reflects the state of cellular health. Its role as an indicator of cellular distress makes it crucial for both diagnostic purposes and understanding the mechanisms of disease. By studying pycnosis and its effects on cellular function, researchers can gain insights into the complexities of life at the cellular level, paving the way for advancements in medical science and therapeutic interventions. As we continue to explore the intricacies of cellular behavior, the importance of processes like pycnosis will undoubtedly remain a focal point in the quest to understand life itself.

在细胞生物学领域,理解细胞在不同生理和病理过程中所经历的各种变化至关重要。其中一种变化被称为pycnosis,指的是细胞核中染色质的浓缩,导致细胞外观缩小。这个过程通常可以在细胞老化、坏死或程序性细胞死亡(即凋亡)期间观察到。pycnosis的重要性不仅在于它作为细胞压力指示剂的作用,还在于它是细胞对压力源反应的基本方面。要理解pycnosis的含义,首先需要了解什么是染色质。染色质是存在于真核细胞核中的DNA和蛋白质的复合体。它的作用是将DNA包装成更紧凑、密集的形状,从而促进基因表达和DNA复制的调控。当细胞经历压力时,无论是来自环境因素、毒素还是缺乏营养,它可能会启动一系列反应,最终导致pycnosis。在pycnosis过程中,染色质变得密集,细胞核缩小。这种形态变化是不可逆细胞损伤的标志。在许多情况下,pycnosis之后会出现其他细胞变化,如核碎裂(karyorrhexis)和核溶解(karyolysis),即细胞核的溶解。这些变化在病理学研究中至关重要,因为它们可以指示疾病的进展,比如癌症,其中细胞调控被破坏。此外,pycnosis可以作为组织病理学检查中的诊断标志。例如,当组织样本在显微镜下分析时,pycnosis的存在可以表明细胞经历了显著的压力或损伤,从而促使进一步调查潜在原因。因此,pycnosis不仅仅是一个细胞现象;它反映了整个生物体的健康状况。除了其病理学意义外,pycnosis在发育生物学中也具有重要意义。在正常胚胎发育过程中,控制的细胞死亡对于塑造组织和器官是必要的。在这种情况下,pycnosis在消除不必要或受损细胞方面发挥了作用,从而有助于生物体的正常形成。总之,pycnosis是细胞生物学中的一个重要概念,反映了细胞健康的状态。它作为细胞压力指示剂的作用使其在诊断目的和理解疾病机制方面至关重要。通过研究pycnosis及其对细胞功能的影响,研究人员可以深入了解生命在细胞层面的复杂性,为医学科学和治疗干预的发展铺平道路。随着我们继续探索细胞行为的复杂性,像pycnosis这样的过程的重要性无疑将继续成为理解生命本身的焦点。