pleiotropy

简明释义

英[plaɪˈɒtrəpi]美[plaɪˈɑːtrəpi]

n. 基因多效性；[遗] 多向性

英英释义

单词用法

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反义词

例句

1.The disposable soma theory and antagonistic pleiotropy theory are examples in which a compensating individual benefit, compatible with classical evolution theory is proposed.

可抛弃体细胞理论和拮抗基因多效性理论都提出了符合经典进化论的补偿性个体受益。

2.The disposable soma theory and antagonistic pleiotropy theory are examples in which a compensating individual benefit, compatible with classical evolution theory is proposed.

可抛弃体细胞理论和拮抗基因多效性理论都提出了符合经典进化论的补偿性个体受益。

3.The major cause of genetic correlation between traits may be due to linkage, or pleiotropy, or both, not pleiotropy only.

不管哪种原因为主，有高度遗传相关（不管是正相关还是负相关）的性状总是可以认为受同一连锁群的基因所控制。

4.The pleiotropy of the five well-studied plant hormones is somewhat analogous to that of certain hormones in animals.

这五种已得到充分研究的植物激素的多效性在某种程度上类似于动物中某些激素的多效性。

5.The disposable soma and antagonistic pleiotropy theories are examples of such thinking.

可抛弃体细胞理论和拮抗基因多效性理论就是这种情况的例子。

6.We hypothesized that germline variation contributes to MPN predisposition and phenotypic pleiotropy.

我们推测种系变异可促进MPN易感及表型多向性。

7.The creation of multiple effects by a single gene is called pleiotropy.

单一基因所产生的多重效应为基因多效性。

8.Research on pleiotropy 多效性 has revealed that some genetic mutations can lead to several unrelated health issues.

对pleiotropy 多效性的研究揭示了一些基因突变可能导致几个无关的健康问题。

9.Geneticists often encounter pleiotropy 多效性 when analyzing the effects of a single gene on various phenotypes.

遗传学家在分析单个基因对各种表型的影响时常常会遇到pleiotropy 多效性。

10.In agriculture, understanding pleiotropy 多效性 can help breeders select for desirable traits without negative side effects.

在农业中，理解pleiotropy 多效性可以帮助育种者选择理想特征而不产生负面副作用。

11.The concept of pleiotropy 多效性 is crucial in understanding how a single gene can influence multiple traits.

单个基因如何影响多个性状的概念是理解pleiotropy 多效性的关键。

12.The study of pleiotropy 多效性 is essential for developing effective treatments for complex diseases.

对pleiotropy 多效性的研究对于开发复杂疾病的有效治疗至关重要。

作文

Pleiotropy is a fascinating concept in genetics that refers to the phenomenon where a single gene influences multiple phenotypic traits. This means that one gene can have several effects on an organism's characteristics, which can sometimes lead to unexpected and complex outcomes. Understanding pleiotropy (基因多效性) is crucial for both genetic research and practical applications in fields such as medicine, agriculture, and evolutionary biology.To illustrate the concept of pleiotropy (基因多效性), consider the example of the gene responsible for sickle cell anemia. This single gene mutation not only causes the production of abnormal hemoglobin, leading to the characteristic sickle-shaped red blood cells but also provides a level of protection against malaria. As a result, individuals who carry one copy of the sickle cell allele may experience both the negative health impacts of sickle cell disease and the positive advantage of reduced malaria susceptibility. This dual effect exemplifies how a single gene can have multiple, sometimes contradictory, effects on an organism's health and survival.In agriculture, pleiotropy (基因多效性) plays a critical role in crop breeding. For instance, a single gene might enhance drought resistance while simultaneously improving yield or nutritional content. Breeders often seek to exploit these pleiotropic effects to develop crops that are more resilient to climate change and better suited to meet the nutritional needs of a growing global population. However, navigating the complexities of pleiotropy (基因多效性) can be challenging, as selecting for one desirable trait may inadvertently affect other traits in unforeseen ways.The implications of pleiotropy (基因多效性) extend beyond genetics into the realm of evolutionary theory. The presence of pleiotropic genes can influence the course of evolution by creating trade-offs among traits. For example, if a gene enhances reproductive success but also increases vulnerability to disease, natural selection may favor different alleles in varying environments. This dynamic interplay illustrates how pleiotropy (基因多效性) can shape the evolutionary trajectory of a species, highlighting the interconnectedness of traits and the complexity of biological systems.Moreover, understanding pleiotropy (基因多效性) is essential for medical research. Many diseases are influenced by multiple genes, and recognizing the pleiotropic effects of certain genes can help researchers identify potential therapeutic targets. For example, a drug designed to mitigate the effects of one genetic condition may inadvertently impact other conditions linked to the same gene. Therefore, a comprehensive understanding of pleiotropy (基因多效性) is vital for developing effective treatment strategies that minimize adverse effects and maximize patient outcomes.In conclusion, pleiotropy (基因多效性) is a key concept in genetics that underscores the complexity of biological systems. By influencing multiple traits, pleiotropic genes can have significant implications for health, agriculture, and evolution. As research continues to unravel the intricacies of pleiotropy (基因多效性), it becomes increasingly clear that a holistic approach is necessary to fully appreciate the interconnectedness of genetic traits and their impact on living organisms. Understanding this concept not only enriches our knowledge of genetics but also informs practical applications that can benefit society as a whole.

基因多效性是遗传学中一个迷人的概念，指的是单个基因影响多个表型特征的现象。这意味着一个基因可以对生物体的特征产生多个影响，这有时会导致意想不到和复杂的结果。理解基因多效性对于遗传研究以及医学、农业和进化生物学等领域的实际应用至关重要。为了说明基因多效性的概念，考虑镰刀型细胞贫血症的基因这一例子。这个单一基因突变不仅导致异常血红蛋白的产生，导致特征性的镰刀形红细胞，而且还提供了一定程度的抗疟疾保护。因此，携带一个镰刀细胞等位基因的个体可能同时经历镰刀细胞疾病的负面健康影响和减少疟疾易感性的积极优势。这种双重效应例证了单个基因如何对生物体的健康和生存产生多重，有时是相互矛盾的影响。在农业中，基因多效性起着关键作用，尤其是在作物育种方面。例如，一个单一基因可能增强抗旱能力，同时提高产量或营养含量。育种者常常试图利用这些多效性效应来开发出更能适应气候变化并更好满足全球人口营养需求的作物。然而，驾驭基因多效性的复杂性可能是具有挑战性的，因为选择一个理想特征可能会无意中影响其他特征，以不可预见的方式。基因多效性的影响超越了遗传学，进入了进化理论的领域。多效性基因的存在可以通过在特征之间创造权衡来影响进化的过程。例如，如果一个基因增强繁殖成功，但同时增加对疾病的脆弱性，自然选择可能会在不同环境中青睐不同的等位基因。这种动态的相互作用说明了基因多效性如何塑造物种的进化轨迹，突显了特征之间的相互联系以及生物系统的复杂性。此外，理解基因多效性对于医学研究至关重要。许多疾病受多个基因的影响，认识到某些基因的多效性效应可以帮助研究人员识别潜在的治疗靶点。例如，旨在减轻一种遗传病影响的药物可能会无意中影响与同一基因相关的其他疾病。因此，全面理解基因多效性对于开发有效的治疗策略至关重要，这些策略可以最小化不良影响并最大化患者结果。总之，基因多效性是遗传学中的一个关键概念，强调了生物系统的复杂性。通过影响多个特征，多效性基因对健康、农业和进化具有重要影响。随着研究不断揭示基因多效性的复杂性，越来越明显的是，全面的方法对于充分理解遗传特征的相互联系及其对生物体的影响是必要的。理解这个概念不仅丰富了我们对遗传学的知识，也为能够惠及整个社会的实际应用提供了信息。