sulfa

简明释义

英[ˈsʌlfə]美[ˈsʌlfə]

adj. 磺胺的；磺胺药剂的

n. 磺胺药物

复 数 s u l f a s

英英释义

单词用法

同义词

反义词

例句

1.The most common drug which caused serious drug eruptions were sulfa-drug and antiepileptics.

重型药疹中以磺胺和抗癫痫药物多见。

2.Any of a group of organic sulfur compounds containing the radical O2NH 2 and including the sulfa drugs.

一种有机硫化合物，含有原子团o2nh2，包括磺胺类药。

3.If he's infected with coccidiosis, he'll need to be treated with specific sulfa-type antibiotics.

如果他与球虫病的感染，他将需要与特定的磺胺类抗生素治疗。

4.Aluminum and its alloy with decorate ceramic oxide coating were developed by secondary oxidation process in sulfa-salicylic acid bath and an organic acid bath.

对铝及铝合金在磺基水杨酸槽液中及另一有机酸槽中进行二次氧化，获得了装饰效果良好的瓷质氧化膜。

5.Patients allergic to sulfa may also be allergic to hydrochlorothiazide because of a similarity in the chemical structure of the medications.

磺胺类药过敏病人也对氢氯噻嗪过敏，因为这两种药物化学结构类似。

6.Organic compounds with sulfur include several amino acids, the sulfa drugs, and many insecticides, solvents, and substances used in making rubber and rayon.

硫的有机化合物包括数种含硫氨基酸、磺胺药以及多种除虫剂、溶剂，以及用于制造橡胶和合成纤维等的许多原料。

7.Some patients are allergic to sulfa 磺胺药 drugs, so it's important to check their medical history.

一些患者对sulfa 磺胺药药物过敏，因此检查他们的病史很重要。

8.A patient with a known sulfa 磺胺药 allergy should avoid certain medications.

已知对sulfa 磺胺药过敏的患者应避免某些药物。

9.The doctor prescribed a course of sulfa 磺胺药 antibiotics to treat the infection.

医生开了一疗程的sulfa 磺胺药抗生素来治疗感染。

10.The pharmacist recommended an alternative to sulfa 磺胺药 for those who have allergies.

药剂师为那些有过敏的人推荐了sulfa 磺胺药的替代品。

11.The use of sulfa 磺胺药 in veterinary medicine has been beneficial for treating bacterial infections.

在兽医学中使用sulfa 磺胺药对治疗细菌感染有益。

作文

The term sulfa refers to a group of synthetic antibiotics that contain sulfonamide, which was one of the first classes of antibiotics developed in the 20th century. These medications have played a crucial role in treating bacterial infections and have saved countless lives since their introduction. The discovery of sulfa drugs can be traced back to the 1930s, when German scientist Gerhard Domagk discovered that a dye called Prontosil could effectively treat streptococcal infections in mice. This groundbreaking finding led to the development of various sulfa compounds that were later used in humans.One of the most significant aspects of sulfa drugs is their mechanism of action. They work by inhibiting the growth of bacteria by interfering with their ability to produce folic acid, which is essential for the synthesis of DNA and RNA. By blocking this pathway, sulfa drugs effectively starve bacteria, preventing them from multiplying and causing further harm to the host. This mechanism of action is particularly effective against a wide range of gram-positive and some gram-negative bacteria, making sulfa drugs versatile in their applications.Despite their effectiveness, sulfa drugs are not without limitations. Over time, many bacteria have developed resistance to these antibiotics, leading to a decline in their efficacy. This has prompted the medical community to explore alternative treatment options and to develop new antibiotics that can combat resistant strains of bacteria. Additionally, some individuals may experience allergic reactions to sulfa drugs, which can range from mild skin rashes to severe anaphylactic reactions. As a result, healthcare providers must carefully consider a patient's medical history before prescribing these medications.In modern medicine, sulfa drugs are often used in combination with other antibiotics to enhance their effectiveness and minimize the risk of resistance. For example, the combination of sulfa drugs with trimethoprim has been widely used to treat urinary tract infections and other bacterial infections. This synergistic effect helps to improve patient outcomes and reduce the likelihood of treatment failure.In conclusion, sulfa drugs represent a significant milestone in the history of medicine. Their discovery paved the way for the development of antibiotics, which have transformed the way we treat bacterial infections. While challenges such as antibiotic resistance and allergic reactions persist, sulfa drugs continue to play a vital role in the fight against infectious diseases. As research progresses, it is essential to remain aware of the potential benefits and limitations of sulfa drugs, ensuring that they are used effectively and responsibly in clinical practice.

“sulfa”这个术语指的是一组含有磺胺的合成抗生素，它是20世纪开发的第一类抗生素之一。这些药物在治疗细菌感染方面发挥了至关重要的作用，自引入以来拯救了无数生命。sulfa药物的发现可以追溯到20世纪30年代，当时德国科学家格哈德·多马克发现一种叫做Prontosil的染料可以有效治疗小鼠的链球菌感染。这一突破性的发现导致了各种sulfa化合物的开发，后者随后被用于人类。sulfa药物的一个重要方面是它们的作用机制。它们通过干扰细菌产生叶酸的能力来抑制细菌的生长，而叶酸对于DNA和RNA的合成至关重要。通过阻断这一途径，sulfa药物有效地使细菌“饥饿”，防止它们繁殖并对宿主造成进一步伤害。这种作用机制特别有效于对多种革兰氏阳性和一些革兰氏阴性细菌，使得sulfa药物在应用上具有广泛的适用性。尽管sulfa药物有效，但它们并非没有局限性。随着时间的推移，许多细菌已经对这些抗生素产生了抗药性，导致其疗效下降。这促使医学界探索替代治疗方案，并开发能够对抗耐药菌株的新抗生素。此外，一些个体可能会对sulfa药物产生过敏反应，反应范围从轻微的皮疹到严重的过敏性休克。因此，医疗提供者在开处方这些药物之前，必须仔细考虑患者的病史。在现代医学中，sulfa药物常常与其他抗生素联合使用，以增强其效果并最小化耐药性的风险。例如，sulfa药物与甲氧苄啶的组合已被广泛用于治疗尿路感染和其他细菌感染。这种协同效应有助于改善患者结果并减少治疗失败的可能性。总之，sulfa药物代表了医学史上的一个重要里程碑。它们的发现为抗生素的发展铺平了道路，彻底改变了我们治疗细菌感染的方式。尽管抗生素耐药性和过敏反应等挑战仍然存在，但sulfa药物继续在对抗传染病方面发挥着重要作用。随着研究的进展，保持对sulfa药物潜在益处和局限性的认识至关重要，确保它们在临床实践中得到有效和负责任的使用。