monogenic

简明释义

英[ˌmɒnəʊˈdʒenɪk]美[ˌmɑːnəˈdʒenɪk]

adj. 单基因的；单性生殖的

英英释义

单词用法

同义词

反义词

例句

1.But study of monogenic diseases can reveal new aspects of genomic biology.

但是，单基因疾病研究能从新的方面揭示基因组生物学。

2.Dr Casanova thinks HSE is the first example of a disease that was thought to be purely infectious but which has turned out to be purely monogenic-that is, under the control of a single gene.

Casanova博士认为HSE的是第一个种原本被认为是单纯的传染性疾病，却最终被证明是被一个单一的基因控制的。

3.Based on the monogenic differentials, cluster and variance analysis method might be applied for the representative isolates selection in the blast resistance evaluation.

在抗病性鉴定中，基于单基因系的代表菌株选择，可考虑应用聚类和变量分析法进行。

4.The strains population was virulent to all 30 rice blast monogenic lines, virulence frequency(VF)ranged from 17.

病菌群体对所测定的30个抗瘟基因均表现出毒性，毒力频率为17。

5.Race specific resistance and field resistance of 30 monogenic rice lines resistant to rice blast, derived from different resources were evaluated.

对来自不同抗源的30个抗稻瘟病单基因系进行了小种专化抗性及田间抗性的分析和评价。

6.Dr Casanova thinks HSE is the first example of a disease that was thought to be purely infectious but which has turned out to be purely monogenic-that is, under the control of a single gene.

Casanova博士认为HSE的是第一个种原本被认为是单纯的传染性疾病，却最终被证明是被一个单一的基因控制的。

7.Cystic fibrosis is an example of a monogenic condition caused by mutations in a single gene.

囊性纤维化是由单一基因突变引起的单基因遗传病的一个例子。

8.The study focused on a rare disease that is known to be monogenic.

这项研究集中在一种已知为单基因遗传的罕见疾病上。

9.Understanding monogenic traits can help in genetic counseling.

理解单基因遗传特征可以帮助进行遗传咨询。

10.The monogenic inheritance pattern simplifies the prediction of disease risk.

这种单基因遗传模式简化了疾病风险的预测。

11.Researchers are investigating monogenic disorders to develop targeted therapies.

研究人员正在调查单基因遗传疾病，以开发针对性的治疗方案。

作文

In the field of genetics, the term monogenic refers to traits or disorders that are determined by a single gene. This concept is crucial for understanding how certain hereditary conditions are passed from one generation to the next. For instance, diseases like cystic fibrosis, sickle cell anemia, and Huntington's disease are all classified as monogenic disorders because they arise from mutations in a single gene. The study of monogenic conditions has significantly advanced our knowledge of human genetics and the mechanisms underlying various diseases.Understanding monogenic disorders is vital not only for geneticists but also for medical professionals who diagnose and treat these conditions. Since these disorders are caused by a single gene, identifying the specific mutation can lead to accurate diagnosis and targeted therapies. For example, advancements in gene therapy have shown promise in treating some monogenic disorders by correcting the defective gene responsible for the disease. This approach highlights the importance of recognizing the monogenic nature of certain conditions, as it opens up new avenues for treatment.Moreover, the implications of monogenic inheritance extend beyond individual patients. Families with a history of monogenic disorders often face difficult decisions regarding family planning. Genetic counseling plays a critical role in providing information about the risks of passing on these conditions to offspring. Couples may choose to undergo genetic testing to determine whether they carry mutations associated with monogenic disorders, allowing them to make informed choices about their reproductive options.The impact of monogenic disorders on public health cannot be underestimated. While each monogenic condition may affect a relatively small number of individuals, collectively, they represent a significant burden on healthcare systems. Research into monogenic disorders is essential for developing effective prevention strategies and improving patient outcomes. By investing in research, we can better understand the genetic basis of these diseases and work towards innovative treatments.In conclusion, the concept of monogenic inheritance is fundamental to the study of genetics and medicine. It encompasses a wide range of disorders that are caused by mutations in single genes, highlighting the complexity and diversity of genetic diseases. As our understanding of monogenic conditions continues to evolve, so too does our ability to diagnose, treat, and prevent these disorders. The future of genetic research holds great promise, and the continued exploration of monogenic disorders will undoubtedly lead to breakthroughs that benefit countless individuals and families affected by these conditions.

在遗传学领域，术语单基因的指的是由单个基因决定的性状或疾病。这个概念对于理解某些遗传病如何从一代传递到下一代至关重要。例如，囊性纤维化、镰状细胞贫血和亨廷顿舞蹈症等疾病都被归类为单基因的疾病，因为它们源于单个基因中的突变。对单基因的病症的研究显著提升了我们对人类遗传学及各种疾病潜在机制的认识。理解单基因的疾病不仅对遗传学家至关重要，也对诊断和治疗这些病症的医疗专业人员至关重要。由于这些疾病是由单个基因引起的，识别特定的突变可以导致准确的诊断和针对性的治疗。例如，基因疗法的进步在治疗一些单基因的疾病方面显示出希望，通过修正导致疾病的缺陷基因。这种方法强调了认识到某些病症的单基因的性质的重要性，因为这为治疗开辟了新的途径。此外，单基因的遗传影响超越了个体患者。拥有单基因的疾病家族史的家庭常常面临关于家庭规划的艰难决定。遗传咨询在提供有关将这些疾病传给后代风险的信息方面发挥着关键作用。夫妻可能会选择进行基因检测，以确定他们是否携带与单基因的疾病相关的突变，从而使他们能够就生育选择做出明智的决定。单基因的疾病对公共健康的影响不容小觑。虽然每种单基因的疾病可能影响相对少数个体，但它们合起来对医疗系统造成了显著负担。对单基因的疾病的研究对于制定有效的预防策略和改善患者结果至关重要。通过对研究的投资，我们可以更好地理解这些疾病的遗传基础，并努力开发创新的治疗方法。总之，单基因的遗传概念是遗传学和医学研究的基础。它涵盖了一系列由单个基因突变引起的疾病，突显了遗传疾病的复杂性和多样性。随着我们对单基因的病症理解的不断发展，我们在诊断、治疗和预防这些疾病的能力也在不断提高。遗传研究的未来充满希望，对单基因的疾病的持续探索无疑将导致突破，造福无数受到这些疾病影响的个人和家庭。