sulphanilamide

简明释义

英[ˌsʌlfəˈnɪləmaɪd]美[sʌlfəˈnɪləmaɪd]

n. 磺胺；对氨基苯磺酰胺

英英释义

单词用法

同义词

反义词

例句

1.Hind of profess to convinced is easy decompose inside bowel reach 5 - amino salicylic acid for sulphanilamide pyridine, to colonic wall the organization has affinity, have antiphlogistic effect.

口服后易在肠内分解为磺胺吡啶及5-氨基水杨酸，对结肠壁组织有亲合力，起到消炎作用。

2.Hind of profess to convinced is easy decompose inside bowel reach 5 - amino salicylic acid for sulphanilamide pyridine, to colonic wall the organization has affinity, have antiphlogistic effect.

口服后易在肠内分解为磺胺吡啶及5-氨基水杨酸，对结肠壁组织有亲合力，起到消炎作用。

3.After the introduction of sulphanilamide, many lives were saved during the early 20th century.

在20世纪初，磺胺酰胺的引入拯救了许多生命。

4.The doctor prescribed sulphanilamide to treat the bacterial infection.

医生开了磺胺酰胺来治疗细菌感染。

5.Pharmacists often have to explain how sulphanilamide works to patients.

药剂师常常需要向患者解释磺胺酰胺的作用原理。

6.The side effects of sulphanilamide can include nausea and skin rashes.

磺胺酰胺的副作用可能包括恶心和皮疹。

7.In the lab, we are studying the effects of sulphanilamide on various pathogens.

在实验室，我们正在研究磺胺酰胺对各种病原体的影响。

作文

The discovery of antibiotics has revolutionized the field of medicine, and one of the earliest compounds that played a significant role in this transformation is sulphanilamide. This synthetic drug, which belongs to the class of sulfonamides, was first introduced in the 1930s. The impact of sulphanilamide on medical treatment cannot be overstated, as it marked the beginning of a new era in the fight against bacterial infections.Before the advent of sulphanilamide, bacterial infections were often fatal, and there were limited options for treatment. Physicians relied heavily on surgical interventions and the body's natural immune response to combat infections. However, with the introduction of sulphanilamide, doctors gained a powerful tool to treat a variety of infections effectively. It works by inhibiting the growth of bacteria, thereby allowing the immune system to eliminate the infection more efficiently.The mechanism of action of sulphanilamide is fascinating. It mimics para-aminobenzoic acid (PABA), a substance that bacteria need to synthesize folic acid, which is essential for their growth and reproduction. By blocking the utilization of PABA, sulphanilamide effectively starves the bacteria, leading to their death or stunted growth. This unique mechanism not only showcases the ingenuity of medicinal chemistry but also highlights the importance of understanding bacterial metabolism in developing antibiotics.Despite its effectiveness, the use of sulphanilamide was not without complications. Some patients experienced allergic reactions, and the emergence of resistant bacterial strains soon became a concern. These challenges underscored the necessity for ongoing research and development in the field of antibiotics. Nevertheless, sulphanilamide paved the way for the discovery of more advanced sulfonamides and other antibiotic classes, contributing significantly to modern medicine.In addition to its medical applications, sulphanilamide has also been utilized in various scientific studies to understand bacterial resistance mechanisms. Researchers have explored how bacteria adapt to the presence of sulphanilamide and develop resistance, leading to the identification of new targets for antibiotic development. This ongoing research is crucial, especially in an era where antibiotic resistance poses a significant threat to public health.Moreover, sulphanilamide serves as a reminder of the importance of responsible antibiotic use. The overprescription and misuse of antibiotics can lead to increased resistance, making it vital for healthcare professionals to prescribe these medications judiciously. Education and awareness among patients about the appropriate use of antibiotics are equally important in combating the rise of resistant strains.In conclusion, sulphanilamide represents a landmark in the history of medicine. Its introduction not only transformed the treatment of bacterial infections but also sparked a wave of research that continues to influence antibiotic development today. Understanding the significance of sulphanilamide helps us appreciate the complexities of microbial resistance and the ongoing efforts required to stay ahead in the battle against infectious diseases. As we move forward, it is essential to learn from the lessons of the past and ensure that the advancements in antibiotic therapy are used wisely and effectively for future generations.

抗生素的发现彻底改变了医学领域，其中一种在这一转变中发挥重要作用的早期化合物是sulphanilamide。这种合成药物属于磺胺类药物，于20世纪30年代首次引入。sulphanilamide对医学治疗的影响不可低估，因为它标志着与细菌感染斗争的新纪元的开始。在sulphanilamide问世之前，细菌感染往往是致命的，治疗选择非常有限。医生主要依靠外科手术和身体的自然免疫反应来对抗感染。然而，随着sulphanilamide的引入，医生获得了一种强有力的工具，可以有效地治疗各种感染。它通过抑制细菌的生长，从而使免疫系统能够更有效地消除感染。sulphanilamide的作用机制令人着迷。它模仿对氨基苯甲酸（PABA），这是细菌合成叶酸所需的一种物质，而叶酸对于细菌的生长和繁殖至关重要。通过阻止PABA的利用，sulphanilamide有效地使细菌“饥饿”，导致其死亡或生长受阻。这一独特机制不仅展示了药物化学的巧妙，还强调了理解细菌代谢在开发抗生素中的重要性。尽管sulphanilamide有效，但其使用并非没有并发症。有些患者出现过敏反应，而耐药细菌株的出现很快成为一个问题。这些挑战突显了在抗生素领域进行持续研究和开发的必要性。尽管如此，sulphanilamide为更先进的磺胺类药物和其他抗生素类别的发现铺平了道路，对现代医学做出了重要贡献。除了医疗应用外，sulphanilamide还被用于各种科学研究，以了解细菌耐药机制。研究人员探讨了细菌如何适应sulphanilamide的存在并发展出耐药性，从而识别新的抗生素开发靶点。这项持续的研究至关重要，尤其是在抗生素耐药性对公共健康构成重大威胁的时代。此外，sulphanilamide提醒我们负责任使用抗生素的重要性。抗生素的过度处方和滥用可能导致耐药性的增加，因此医疗专业人员在开处方时必须谨慎。提高患者对抗生素适当使用的教育和意识同样重要，这对于打击耐药菌株的上升势头至关重要。总之，sulphanilamide代表了医学史上的一个里程碑。它的引入不仅改变了细菌感染的治疗方式，还激发了一波研究浪潮，这一浪潮至今仍在影响抗生素的发展。理解sulphanilamide的重要性帮助我们欣赏微生物耐药性的复杂性，以及保持领先于传染病斗争所需的持续努力。在未来的发展中，学习过去的教训，确保抗生素治疗的进步得到明智和有效的使用，对于未来几代人至关重要。