chimerism

简明释义

英[kaɪˈmɪərɪzəm]美[ˈkaɪməˌrɪzəm]

n. 嵌合性；[遗] 嵌合现象

英英释义

单词用法

同义词

反义词

例句

1.Conclusion: Chimerism and immune tolerance can be induced by Cyclophosphmide and when the grafted skin was rejected, the ratio of t cells from BN significantly decreased.

结论：环磷酰胺可诱导嵌合免疫耐受的产生，在嵌合状态下可检测到供鼠来源的T细胞。当移植皮肤被排斥时，供鼠来源T细胞占总t细胞的比例显著降低。

2.The aim of this study was to analyze the hematopoietic chimerism after non-myeloablative allogeneic peripheral blood stem cell transplantation (NAPBSCT).

本研究旨在探讨非清髓异基因外周血造血干细胞移植(NAPBSCT)后造血嵌合体的临床意义。

3.Objective To assessed the ability of FK506 and antilymphocyte serum(ALS) to induce mixed chimerism and tolerance for knee composite tissue allograft in rabbits without chronic immunosuppression.

目的探讨短期使用FK5 0 6和抗淋巴细胞血清（ALS）诱导兔同种异体膝关节移植嵌合耐受的作用。

4.The research focuses on a specific aspect of chimerism that would involve removing the nucleus from animal egg cells and replacing it with human DNA.

研究主要集中在嵌合状态的一个特殊方面，即将动物卵细胞的核取出后置入人类DNA。

5.The median time to full donor myeloid cell and T cell chimerism was 4 and 8 weeks respectively.

全部供者粒细胞嵌合体形成中位时间为4周，全部供者T细胞形成中位时间为8周。

6.Some experimental protocols were introduced including mixed chimerism of allogeneic bone marrow, blockade of co-stimulation signal and transgene technology for transplantation tolerance induction.

介绍一些具体方案，包括建立异基因骨髓嵌合体、阻断T细胞活化第二信号和转基因技术诱导移植免疫耐受。

7.CONCLUSION: Donor specific bone marrow infusion enhances chimerism formation in bone marrow, alleviates the rejection of liver allotransplantation and improve survival of liver allotransplantation.

结论：供体骨髓输注可形成供受体细胞的嵌合状态，可降低同种异体肝移植的排斥反应，延长受体生存时间。

8.Conclusion it suggested that molecular monitoring of the early dynamics of chimerism after NAST could be useful in predicting engraftment, or rejection.

结论NAST早期造血细胞嵌合体检测及确定ME对判断植入、预测移植排斥具有重要意义。

9.CONCLUSION: Donor specific bone marrow infusion enhances chimerism formation in bone marrow, alleviates the rejection of liver allotransplantation and improve survival of liver allotransplantation.

结论：供体骨髓输注可形成供受体细胞的嵌合状态，可降低同种异体肝移植的排斥反应，延长受体生存时间。

10.The phenomenon of chimerism 嵌合体状态 can complicate genetic testing and organ transplantation procedures.

嵌合体状态现象可能会使基因检测和器官移植程序变得复杂。

11.In certain species of lizards, researchers have observed instances of chimerism 嵌合体状态, where individuals possess cells from different genetic origins.

在某些蜥蜴物种中，研究人员观察到嵌合体状态的实例，其中个体拥有来自不同遗传来源的细胞。

12.Researchers study chimerism 嵌合体状态 in plants to understand how hybrid vigor occurs.

研究人员研究植物中的嵌合体状态以了解杂交优势是如何发生的。

13.Some cases of human chimerism 嵌合体状态 have been documented, leading to unique medical challenges.

一些人类嵌合体状态的案例已经被记录下来，导致独特的医学挑战。

14.Understanding chimerism 嵌合体状态 is crucial for developing effective treatments for certain cancers.

理解嵌合体状态对开发某些癌症的有效治疗至关重要。

作文

Chimerism is a fascinating biological phenomenon that occurs when an individual possesses two or more genetically distinct cell lines. This can happen in various ways, such as through the fusion of embryos during early development or through organ transplantation. The term 'chimerism' derives from the Greek mythological creature, the Chimera, which was composed of parts from different animals. In the same way, individuals with chimerism (嵌合体) exhibit a unique genetic mosaic that can have significant implications for their health and identity.One of the most well-known examples of chimerism (嵌合体) is seen in certain cases of human twins. When two embryos fuse together in the womb, the resulting individual may carry cells from both original embryos. This can lead to interesting genetic outcomes, such as one twin having a different blood type than the other or even possessing different physical traits. In some rare instances, these chimeric individuals may not even be aware of their condition until they undergo genetic testing.In the medical field, chimerism (嵌合体) plays a crucial role, particularly in organ transplantation. When a patient receives an organ from a donor, the recipient's body may recognize the new cells as foreign. However, if the transplanted organ contains cells from the recipient's own body, this can lead to a state of chimerism (嵌合体), where the immune system is less likely to reject the organ. This phenomenon has opened up new avenues for research into improving transplant success rates and understanding the immune response.Moreover, chimerism (嵌合体) can also be observed in some animal species. For instance, certain fish and amphibians are known to exhibit natural chimerism, where they possess cells from different genetic backgrounds. This has prompted scientists to study these organisms to better understand the mechanisms behind chimerism (嵌合体) and its potential applications in medicine and genetics.The implications of chimerism (嵌合体) extend beyond biology and medicine; they also touch on ethical and philosophical questions. For example, if an individual has cells from a different genetic background, what does this mean for their identity? How should society view individuals who are genetically diverse in such a profound way? These questions challenge our understanding of individuality and raise important discussions about genetic identity in the modern world.In conclusion, chimerism (嵌合体) is a complex and intriguing concept that spans multiple disciplines, including biology, medicine, and ethics. As research continues to uncover the mysteries of chimerism (嵌合体), we may find new ways to leverage this phenomenon for advancements in healthcare while simultaneously grappling with the philosophical implications it presents. Understanding chimerism (嵌合体) is not only vital for scientific progress but also essential for fostering a broader conversation about what it means to be human in an age of increasing genetic complexity.

嵌合体是一种引人入胜的生物现象，发生在一个个体拥有两种或多种基因不同的细胞系时。这种情况可以通过多种方式发生，例如在早期发育过程中胚胎的融合或器官移植。术语“嵌合体”源于希腊神话中的生物奇美拉，它由不同动物的部分组成。同样，具有chimerism（嵌合体）特征的个体表现出独特的基因马赛克，这可能对他们的健康和身份产生重大影响。最著名的chimerism（嵌合体）例子之一是在某些人类双胞胎中。当两个胚胎在子宫中融合时，最终形成的个体可能携带来自两个原始胚胎的细胞。这可能导致有趣的遗传结果，例如一个双胞胎的血型与另一个不同，甚至拥有不同的身体特征。在一些罕见的情况下，这些嵌合体个体可能直到进行基因检测时才意识到自己的状况。在医学领域，chimerism（嵌合体）起着至关重要的作用，特别是在器官移植中。当患者接受来自捐赠者的器官时，接受者的身体可能会将新细胞视为外来物。然而，如果移植的器官包含来自接受者自身的细胞，则可能导致一种chimerism（嵌合体）状态，在这种状态下，免疫系统不太可能排斥该器官。这一现象为改善移植成功率和理解免疫反应开辟了新的研究方向。此外，某些动物物种中也可以观察到chimerism（嵌合体）。例如，某些鱼类和两栖动物被发现具有自然的嵌合体特征，它们拥有来自不同遗传背景的细胞。这促使科学家研究这些生物，以更好地理解chimerism（嵌合体）背后的机制及其在医学和遗传学中的潜在应用。chimerism（嵌合体）的影响超越了生物学和医学，还涉及伦理和哲学问题。例如，如果一个个体拥有来自不同遗传背景的细胞，这对他们的身份意味着什么？社会应该如何看待这种在基因上如此深刻多样化的个体？这些问题挑战了我们对个体性的理解，并引发了关于现代世界中遗传身份的重要讨论。总之，chimerism（嵌合体）是一个复杂而引人入胜的概念，跨越生物学、医学和伦理等多个学科。随着研究不断揭示chimerism（嵌合体）的奥秘，我们可能会找到利用这一现象推动医疗进步的新方法，同时也面临着它所带来的哲学影响。理解chimerism（嵌合体）不仅对科学进步至关重要，而且对于促进关于在日益复杂的遗传时代中成为人类的更广泛讨论也是必要的。