tumorigenicity

简明释义

英[ˌtjuːmərɪdʒɪˈnɪsɪti]美[ˌtuməˌrɪdʒəˈnɪsɪti]

n. 致肿瘤性；肿瘤发生学

英英释义

单词用法

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反义词

例句

1.The carcinogenicity of nickel compounds on human epithelial cells was identified by transforming assay, assay for culture on soft AGAR and test of tumorigenicity in nude mice.

研究几种镍化合物对培养人支气管上皮细胞的恶性转化作用及转化细胞的致癌性。

2.Objective To explore Insulin like growth factor 1 receptor(IGF 1R)gene quantitative expression in human pancreatic cancer cells(PC 3) and the relationship of IGF 1R with apoptosis?tumorigenicity.

目的探讨胰腺癌细胞（PC-3）胰岛素样生长因子-1受体（IGF- 1R）基因的定量表达，及其与细胞凋亡、成瘤性的关系。

3.Objective To study the tumorigenicity and metastasis of poorly immunogenic murine B16 melanoma cells transfected with murine interleukin12 (IL12) gene.

目的探讨白细胞介素12（IL12）基因转移对弱免疫原性的小鼠B16黑色素瘤细胞生长与转移的影响。

4.MTT method was used to measure proliferation capacity and sensitivity to chemotherapeutic drugs, and tumorigenicity was measured by transplanted into the nude mice.

MTT法检测克隆球细胞和贴壁细胞的增殖能力和对化疗药的敏感性，并植入裸鼠皮下比较移植瘤形成能力；

5.Objective to study the influence on tumorigenicity of human renal cell carcinoma (RCC) cells transduced with human IL 2 gene, and to intend in forming a basis for RCC gene therapy.

目的研究转人IL2基因对原代肾细胞癌(RCC)细胞致瘤性的影响，为RCC的基因治疗提供依据。

6.Tumor metastasis suppressor gene is a kind of genes that only suppresses metastasis without affecting tumorigenicity and tumor growth.

癌转移抑制基因是一类只抑制癌细胞的转移而不影响肿瘤的发生与生长的基因。

7.Results Cell growth in vitro and tumorigenicity in nude mice were inhibited dramatically by garlic oil.

结果大蒜油对癌细胞形态、增殖和致瘤性有明显影响。

8.Soft agar assay and nude mouse tumorigenicity assay were carried out.

软琼脂集落形成试验和裸鼠成瘤试验。

9.Objective To explore Insulin like growth factor 1 receptor(IGF 1R)gene quantitative expression in human pancreatic cancer cells(PC 3) and the relationship of IGF 1R with apoptosis?tumorigenicity.

目的探讨胰腺癌细胞（PC-3）胰岛素样生长因子-1受体（IGF- 1R）基因的定量表达，及其与细胞凋亡、成瘤性的关系。

10.Scientists are exploring how genetic modifications affect the tumorigenicity of stem cells.

科学家们正在探索基因修饰如何影响干细胞的肿瘤发生性。

11.The tumorigenicity of the virus was confirmed through multiple in vivo experiments.

通过多项体内实验确认了该病毒的肿瘤发生性。

12.The researchers conducted a study to assess the tumorigenicity of the new drug in animal models.

研究人员进行了一项研究，以评估新药在动物模型中的肿瘤发生性。

13.Understanding the mechanisms of tumorigenicity can help develop better cancer therapies.

理解肿瘤发生性的机制可以帮助开发更好的癌症疗法。

14.High levels of certain chemicals have been linked to increased tumorigenicity in laboratory tests.

某些化学物质的高水平与实验室测试中增加的肿瘤发生性有关。

作文

The study of cancer has led to significant advancements in our understanding of the mechanisms that drive tumor growth and development. One critical aspect of this research is the concept of tumorigenicity, which refers to the ability of a substance or cell to form tumors. Understanding tumorigenicity is essential for developing effective cancer therapies and preventive measures. In recent years, scientists have focused on identifying the factors that contribute to the tumorigenicity of various cells, including genetic mutations, environmental influences, and cellular interactions.One important area of research involves the role of stem cells in tumorigenicity. Stem cells have the unique ability to differentiate into various cell types, which makes them vital for tissue regeneration. However, certain conditions can lead to the transformation of normal stem cells into cancerous cells, thereby increasing their tumorigenicity. Researchers are investigating how specific signaling pathways and genetic alterations can enhance the tumorigenicity of these cells, ultimately leading to the formation of tumors.Another factor that affects tumorigenicity is the microenvironment surrounding the tumor. Tumors do not exist in isolation; they interact with surrounding tissues, blood vessels, and immune cells. This interaction can either promote or inhibit tumorigenicity. For instance, a supportive microenvironment can provide the necessary nutrients and signals that encourage tumor growth. Conversely, an unfavorable microenvironment may suppress tumorigenicity by activating immune responses that target cancer cells.Furthermore, the study of tumorigenicity extends beyond just the biological aspects; it also encompasses the implications for public health. Understanding the factors that influence tumorigenicity can help in the development of screening programs and preventive strategies aimed at reducing cancer incidence. For example, identifying environmental carcinogens that increase tumorigenicity can lead to policy changes that protect populations from exposure to harmful substances.In conclusion, tumorigenicity is a multifaceted concept that plays a crucial role in cancer research and treatment. By studying the factors that contribute to tumorigenicity, scientists can gain valuable insights into tumor biology, leading to improved therapeutic approaches and better outcomes for patients. As research continues to evolve, the hope is that a deeper understanding of tumorigenicity will pave the way for innovative strategies to combat cancer effectively.

癌症研究的进展使我们对驱动肿瘤生长和发展的机制有了重要的理解。这个研究中的一个关键方面是“tumorigenicity”的概念，它指的是某种物质或细胞形成肿瘤的能力。理解tumorigenicity对开发有效的癌症治疗和预防措施至关重要。近年来，科学家们专注于识别导致各种细胞tumorigenicity的因素，包括基因突变、环境影响和细胞相互作用。一个重要的研究领域涉及干细胞在tumorigenicity中的作用。干细胞具有分化为各种细胞类型的独特能力，这使它们对组织再生至关重要。然而，在某些条件下，正常干细胞可能转化为癌细胞，从而增加其tumorigenicity。研究人员正在调查特定信号通路和基因改变如何增强这些细胞的tumorigenicity，最终导致肿瘤的形成。影响tumorigenicity的另一个因素是肿瘤周围的微环境。肿瘤并不是孤立存在的；它们与周围组织、血管和免疫细胞相互作用。这种相互作用可以促进或抑制tumorigenicity。例如，一个支持性的微环境可以提供必要的营养和信号，鼓励肿瘤生长。相反，一个不利的微环境可能通过激活针对癌细胞的免疫反应来抑制tumorigenicity。此外，tumorigenicity的研究不仅涉及生物学方面；它还包括对公共健康的影响。理解影响tumorigenicity的因素可以帮助开发筛查程序和预防策略，旨在减少癌症的发生率。例如，识别增加tumorigenicity的环境致癌物可以导致政策改变，以保护人群免受有害物质的暴露。总之，tumorigenicity是一个多方面的概念，在癌症研究和治疗中发挥着至关重要的作用。通过研究影响tumorigenicity的因素，科学家们可以获得肿瘤生物学的宝贵见解，从而改善治疗方法，提高患者的治疗效果。随着研究的不断发展，希望对tumorigenicity的更深入理解将为有效抗击癌症铺平道路。