racemic

简明释义

英[rəˈsiːmɪk;rəˈsemɪk]美[rəˈsemɪk]

adj. 外消旋的；消旋酸的

英英释义

单词用法

同义词

反义词

例句

1.The membranes were then used in the electrodialysis resolution process to separate DL-4-hydroxyphenylglycine racemic mixture.

将其用于拆分DL-对羟基苯甘氨酸外消旋混合物的电渗析过程。

2.Presently, most of the catalysts used for the resolution of racemic mixtures are hydrolases, especially lipases.

目前，用于拆分外消旋化合物的酶多数是水解酶，而且绝大多数为脂肪酶。

3.The dynamic kinetic resolution (DKR) of racemic compounds provides one of the most convenient and efficient routes to a wide range of enantiomerically enriched molecules.

动态动力学拆分是合成具有光学活性化合物最方便和最有效的方法之一。

4.The main route for obtaining optically active alcohols is resolution of racemic alcohols catalyzed by enzyme in organic solvents by the esterification reaction.

有机相中应用酯化反应，酶法催化拆分消旋醇是获得光学活性醇的重要途径。

5.In conclusion, the new chiral derivatizing agent, AFGIT, is not only useful to resolve the racemic amine drugs or amino acids but also to enhance their detection sensitivity by the developed methods.

结论，本研究所开发之新光学衍生剂AFGIT能有效的分离 混旋性胺类药物或胺基酸，并且增加它们的侦测灵敏度。

6.When considering biocatalysis, terms like kinetic racemic resolution or chiral syntheses immediately come to mind.

提到生物催化，我们通常会想到外消旋物的动力学拆分和手性合成。

7.At the same time, this paper also split the R-isomer of racemic to change and re-recovery.

同时本论文也对拆分后的R型异构体进行转变消旋而重回收。

8.Use of stereoselective or stereospecific synthetic methods or separation of racemic mixtures can be used to obtain individual optical isomers.

可以使用立体选择或立体专一的合成方法，或者外消旋混合物的分离，来获得单独的光学异构体。

9.In pharmaceutical research, the racemic 外消旋的 mixture of a drug can have different effects than its pure enantiomers.

在药物研究中，药物的racemic 外消旋的 混合物可能与其纯对映体有不同的效果。

10.The chemist synthesized a new compound that was found to be racemic 外消旋的 in nature.

这位化学家合成了一种新化合物，发现它在性质上是racemic 外消旋的。

11.The racemic 外消旋的 form of the substance was easier to produce in the laboratory.

这种物质的racemic 外消旋的 形式在实验室中更容易生产。

12.The racemic 外消旋的 acid was isolated from natural sources for further analysis.

这种racemic 外消旋的 酸是从自然来源中分离出来以进行进一步分析。

13.Researchers are studying the effects of racemic 外消旋的 mixtures on human metabolism.

研究人员正在研究racemic 外消旋的 混合物对人类新陈代谢的影响。

作文

In the field of chemistry, the term racemic refers to a mixture that contains equal amounts of two enantiomers, which are molecules that are mirror images of each other. This concept is particularly important in the study of chiral compounds, which can exist in two forms that are non-superimposable. The significance of racemic mixtures extends beyond theoretical chemistry; they play a crucial role in pharmaceuticals and drug development. Many drugs are chiral, meaning that their efficacy and safety can vary significantly between the two enantiomers. For example, one enantiomer might be therapeutically beneficial, while the other could be harmful or ineffective. Therefore, understanding racemic mixtures is essential for chemists and pharmacologists alike.The process of creating a racemic mixture often occurs during the synthesis of chiral compounds. When a reaction produces both enantiomers without favoring one over the other, the result is a racemic mixture. This can be seen in various chemical reactions, including those involving asymmetric synthesis, where the goal is to produce one specific enantiomer. Researchers have developed numerous methods to resolve racemic mixtures into their individual components, a process known as resolution. Techniques such as chromatography or the use of chiral catalysts are commonly employed to achieve this separation.The implications of racemic mixtures are not limited to chemistry alone. In the realm of medicine, the presence of racemic forms can lead to complex challenges. For instance, a well-known case is that of thalidomide, a drug that was originally marketed as a racemic mixture. One enantiomer provided the desired sedative effects, while the other caused severe birth defects when taken by pregnant women. This tragic outcome highlighted the importance of studying racemic mixtures and understanding the different effects that each enantiomer can have on the body.Moreover, the pharmaceutical industry has made significant strides in developing enantiomerically pure drugs, which are designed to contain only one of the two enantiomers. This approach not only enhances the therapeutic effect but also minimizes potential side effects associated with the other enantiomer present in a racemic mixture. As a result, many new drugs are now developed with a focus on chirality, leading to safer and more effective treatments for various medical conditions.In conclusion, the term racemic encapsulates a fundamental concept in chemistry that has far-reaching implications in drug development and medical practice. Understanding racemic mixtures and their properties allows chemists and healthcare professionals to better navigate the complexities of chiral compounds. As research continues to advance, the knowledge surrounding racemic mixtures will undoubtedly play a pivotal role in the future of pharmaceuticals, leading to improved patient outcomes and enhanced therapeutic strategies. Thus, the study of racemic compounds is not merely an academic exercise; it is a vital aspect of modern science that impacts the health and well-being of individuals worldwide.

在化学领域，术语racemic指的是一种混合物，包含两种对映体的相等数量，对映体是彼此的镜像分子。这个概念在手性化合物的研究中尤为重要，手性化合物可以以两种形式存在，这些形式是不可叠加的。racemic混合物的重要性超越了理论化学；它们在制药和药物开发中发挥着关键作用。许多药物是手性的，这意味着它们的疗效和安全性在两个对映体之间可能会显著不同。例如，一个对映体可能具有治疗效果，而另一个可能有害或无效。因此，理解racemic混合物对于化学家和药理学家来说至关重要。创建racemic混合物的过程通常发生在手性化合物的合成过程中。当反应产生两种对映体而不偏向于其中一个时，结果就是racemic混合物。这可以在各种化学反应中看到，包括那些涉及不对称合成的反应，其目标是生产一个特定的对映体。研究人员已经开发出许多方法来将racemic混合物分解为其各个组成部分，这个过程称为分离。色谱法或使用手性催化剂等技术通常用于实现这种分离。racemic混合物的影响不仅限于化学。在医学领域，racemic形式的存在可能导致复杂的挑战。例如，一个众所周知的案例是沙利度胺，这是一种最初作为racemic混合物上市的药物。一个对映体提供了所需的镇静效果，而另一个在怀孕女性服用时导致严重的出生缺陷。这一悲惨的结果突显了研究racemic混合物及理解每个对映体对身体的不同影响的重要性。此外，制药行业在开发对映体纯净药物方面取得了重大进展，这些药物旨在仅包含两个对映体中的一个。这种方法不仅增强了治疗效果，还最小化了与racemic混合物中另一对映体相关的潜在副作用。因此，许多新药现在都专注于手性，导致对各种医疗条件的治疗更加安全和有效。总之，术语racemic概括了化学中的一个基本概念，该概念在药物开发和医学实践中具有深远的影响。理解racemic混合物及其特性使化学家和医疗专业人员能够更好地应对手性化合物的复杂性。随着研究的不断推进，围绕racemic混合物的知识无疑将在未来的制药领域发挥关键作用，从而改善患者的治疗结果并增强治疗策略。因此，研究racemic化合物不仅仅是一个学术练习；它是现代科学的一个重要方面，影响着全球个人的健康和福祉。