sphingosine

简明释义

英[ˈsfɪŋgə(ʊ)saɪn]美[ˈsfɪŋɡəsɪn]

n. 鞘氨醇；神经胺

英英释义

单词用法

同义词

反义词

例句

1.Sphingosine 1 phosphate (SPP) is an important second messenger involved in cell growth and cell death.

鞘氨醇1磷酸(SPP)是重要的细胞第二信使，影响细胞的生长和死亡。

2.Herein we review the chemical studies on sphingosine and related lipid derivatives, with focus on their chemical synthesis.

本文主要综述了鞘氨醇等衍生脂质的化学研究，特别是它们的化学合成进展。

3.Sphingosine kinase (SPK) is a key enzyme catalyzing the formation of sphingosine 1 phosphate (S1P), which is a lipid messenger with strong angiogenic activity.

细胞内鞘氨醇激酶（SPK）是催化鞘氨醇生成1-磷酸鞘氨醇（S1P）的限速酶。

4.Objective To investigate the effect and mechanism of sphingosine 1-phosphate (S1P) on action potential (AP) and voltage-dependent potassium current (KV) in isolated guinea pig ventricular myocytes.

目的研究1 -磷酸鞘氨醇(S1P)对豚鼠心室肌细胞动作电位(AP)及电压依赖性钾电流(KV)的作用及其机制。

5.Objective To investigate the effect and mechanism of sphingosine 1-phosphate (S1P) on action potential (AP) and voltage-dependent potassium current (KV) in isolated guinea pig ventricular myocytes.

目的研究1 -磷酸鞘氨醇(S1P)对豚鼠心室肌细胞动作电位(AP)及电压依赖性钾电流(KV)的作用及其机制。

6.In the context of cancer research, sphingosine is being explored as a potential therapeutic target.

在癌症研究中，sphingosine（神经酰胺）被探索作为潜在的治疗靶点。

7.The role of sphingosine in cell signaling is crucial for understanding cellular processes.

理解细胞过程时，sphingosine（神经酰胺）在细胞信号传导中的作用至关重要。

8.Researchers are studying how sphingosine affects inflammation in various diseases.

研究人员正在研究sphingosine（神经酰胺）如何影响各种疾病中的炎症。

9.The conversion of ceramide to sphingosine is an important biochemical pathway.

神经酰胺转化为sphingosine（神经酰胺）的过程是一个重要的生化途径。

10.Elevated levels of sphingosine can indicate certain metabolic disorders.

升高的sphingosine（神经酰胺）水平可能表明某些代谢紊乱。

作文

Sphingosine is a vital molecule in the field of biochemistry and cell biology. It is an amino alcohol with a long hydrocarbon chain that plays a crucial role in the structure and function of cell membranes. The significance of sphingosine (鞘氨醇) lies in its ability to form sphingolipids, which are essential components of cellular membranes. Sphingolipids are not only structural elements but also participate in signaling pathways that regulate various cellular processes, including cell growth, differentiation, and apoptosis.The discovery of sphingosine (鞘氨醇) dates back to the late 19th century when it was first isolated from animal tissues. Since then, extensive research has been conducted to understand its biological functions and implications in health and disease. For instance, alterations in sphingolipid metabolism, which involves sphingosine (鞘氨醇), have been linked to several diseases, including cancer, diabetes, and neurodegenerative disorders.One of the fascinating aspects of sphingosine (鞘氨醇) is its role as a signaling molecule. It can be phosphorylated to form sphingosine-1-phosphate (S1P), a potent lipid mediator that influences various physiological processes. S1P is involved in regulating immune responses, vascular permeability, and neuronal signaling. This highlights the importance of sphingosine (鞘氨醇) not just as a structural component of cells but also as a key player in cellular communication.Moreover, the study of sphingosine (鞘氨醇) has opened up new avenues for therapeutic interventions. Researchers are exploring ways to manipulate sphingolipid metabolism to develop treatments for diseases where these pathways are disrupted. For example, drugs targeting sphingosine-1-phosphate receptors are being investigated for their potential in treating autoimmune diseases and cancer.In conclusion, sphingosine (鞘氨醇) is much more than a simple molecule; it is a critical player in the intricate web of cellular functions. Its role in forming sphingolipids and acting as a signaling molecule underscores its importance in both health and disease. As research continues to unravel the complexities of sphingosine (鞘氨醇) and its derivatives, we can anticipate significant advancements in our understanding of cellular biology and the development of novel therapeutic strategies. Understanding sphingosine (鞘氨醇) is essential for anyone interested in the biochemical foundations of life and the potential for medical breakthroughs in the future.

鞘氨醇是生物化学和细胞生物学领域的重要分子。它是一种具有长碳氢链的氨基醇，在细胞膜的结构和功能中发挥着至关重要的作用。鞘氨醇（sphingosine）的重要性在于它能够形成鞘脂，这些鞘脂是细胞膜的重要组成部分。鞘脂不仅是结构元素，还参与调节各种细胞过程的信号传导途径，包括细胞生长、分化和凋亡。鞘氨醇（sphingosine）的发现可以追溯到19世纪末，当时它首次从动物组织中分离出来。从那时起，进行了广泛的研究，以了解其生物功能及其在健康和疾病中的影响。例如，涉及鞘氨醇（sphingosine）代谢的改变与多种疾病（包括癌症、糖尿病和神经退行性疾病）相关联。鞘氨醇（sphingosine）一个迷人的方面是它作为信号分子的角色。它可以被磷酸化形成鞘氨醇-1-磷酸（S1P），这是一种强效的脂质介质，影响各种生理过程。S1P参与调节免疫反应、血管通透性和神经信号传导。这突显了鞘氨醇（sphingosine）不仅作为细胞的结构组成部分的重要性，也作为细胞通信中的关键角色。此外，对鞘氨醇（sphingosine）的研究为治疗干预开辟了新的途径。研究人员正在探索操控鞘脂代谢的方法，以开发针对这些途径失调的疾病的治疗。例如，针对鞘氨醇-1-磷酸受体的药物正在被研究其在治疗自身免疫疾病和癌症中的潜力。总之，鞘氨醇（sphingosine）不仅仅是一个简单的分子；它是在细胞功能复杂网络中扮演关键角色的分子。它在形成鞘脂和作为信号分子中的作用突出了其在健康和疾病中的重要性。随着研究继续揭示鞘氨醇（sphingosine）及其衍生物的复杂性，我们可以期待对细胞生物学理解的重大进展以及新型治疗策略的发展。理解鞘氨醇（sphingosine）对于任何对生命的生化基础和未来医学突破潜力感兴趣的人来说都是至关重要的。