thromboplastin

简明释义

英[ˌθrɒmbəʊˈplæstɪn]美[ˌθrɑːmbəˈplæstɪn]

n. [生化] 促凝血酶原激酶；血栓形成质

英英释义

单词用法

同义词

反义词

例句

1.The anticoagulant activity of iron heparin nanoparticles were tested by activated partial thromboplastin time (APTT) assay.

通过活化部分凝血激酶时间(APTT)的方法测定肝素铁纳米粒的抗凝血活性。

2.Objective To determine the abnormal result for activated partial thromboplastin time(APTT)by instrument detection with two commercial reagents.

目的探讨仪器法测定活化的部分凝血活酶时间（APTT）的参考范围和异常结果的判定标准。

3.Objective To investigate the effects of different storage temperatures on anticoagulated blood hemagglutination tests, including prothrombin time(PT), and activated partial thromboplastin time(APTT).

目的探讨不同的抗凝血体外贮存条件对凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）的影响。

4.The prothrombin time(PT) and the active partial thromboplastin time(APTT) were measured by the ACL- 200 antomatic blood agglutination instrument.

用ACL-200型血液凝集仪测定大鼠凝血酶原时间（PT）和部分凝血活酶时间（APTT）。

5.Objective The aim of this study were to evaluate the value of activated partial thromboplastin time(APTT) in monitoring low-molecular weight heparin(LMWH).

目的进一步探讨活化的部分凝血活酶时间（APTT）对低分子量肝素（LMWH）治疗的实验监测价值。

6.CBC with platelet count, fibrinogen level, partial thromboplastin time, and ABO blood typing and antibody screen are obtained.

全血检查，包括血小板计数、纤维蛋白原水平、部分凝血活酶时间、ABO血型和抗体监测。

7.The PT, PTR and INR of 60 patients treated with oral anticoagulants and 40 patients with liver disorders were determined with the two kinds of thromboplastin reagents.

用进口试剂和自制品测定60例口服华法令抗凝治疗病人和40例肝病患者的PT，求得ptr和INR并进行比较。

8.Objective: To explore clinical significance of detecting prothrombin time (PT), the activated partial thromboplastin time (APTT), thrombin time (TT), plasma fibrinogen (fib) for parturient women.

目的：探讨检测临产孕妇凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)的临床意义。

9.In addition, the serum bilirubin level began to decrease and the partial-thromboplastin time returned to normal.

此外，血清胆红素水平开始下降，部分凝血酶原时间恢复正常。

10.During the surgery, they monitored the levels of thromboplastin 血栓素 to ensure proper clot formation.

在手术过程中，他们监测thromboplastin 血栓素 的水平以确保适当的血块形成。

11.The doctor explained that the presence of thromboplastin 血栓素 in the blood is crucial for the clotting process.

医生解释说，血液中存在的thromboplastin 血栓素 对于凝血过程至关重要。

12.Healthcare providers often use thromboplastin 血栓素 as a reference point in diagnosing clotting disorders.

医疗提供者通常将thromboplastin 血栓素 作为诊断凝血障碍的参考点。

13.The lab test measured the activity of thromboplastin 血栓素 to assess the patient’s coagulation status.

实验室测试测量了thromboplastin 血栓素 的活性，以评估患者的凝血状态。

14.A deficiency in thromboplastin 血栓素 can lead to excessive bleeding.

缺乏thromboplastin 血栓素 可能导致过度出血。

作文

In the realm of medical science, understanding the components of blood coagulation is crucial for both diagnosis and treatment of various disorders. One such essential component is thromboplastin, which plays a pivotal role in the clotting process. Thromboplastin is a complex of proteins that initiates the clotting cascade, ultimately leading to the formation of a blood clot. This process is vital in preventing excessive bleeding when an injury occurs. When we talk about thromboplastin, we often refer to its two main forms: tissue factor (TF) and platelet factor 3 (PF3). Tissue factor is released by damaged tissues and interacts with Factor VII in the blood, activating it to Factor VIIa. This activated form then catalyzes the conversion of Factor X to Xa, which is a key step in the common pathway of coagulation. On the other hand, platelet factor 3, which is released from activated platelets, provides a surface for other coagulation factors to assemble and work effectively.The importance of thromboplastin extends beyond just its role in hemostasis; it is also significant in various clinical settings. For example, in laboratory tests such as the prothrombin time (PT) and activated partial thromboplastin time (aPTT), thromboplastin is used to assess the functionality of the coagulation pathway. Abnormal results in these tests can indicate underlying conditions such as liver disease, vitamin K deficiency, or the presence of anticoagulants in the system.Moreover, the use of thromboplastin in therapeutic contexts cannot be overlooked. In certain cases, patients may require the administration of clotting factors to manage bleeding disorders like hemophilia. Understanding how thromboplastin interacts with other components of the coagulation cascade can help healthcare providers make informed decisions regarding treatment options.In recent years, research has also focused on the role of thromboplastin in more complex conditions such as thromboembolism. The inappropriate activation of the coagulation cascade can lead to the formation of clots that obstruct blood flow, resulting in serious complications such as strokes or heart attacks. Therefore, studying thromboplastin and its mechanisms can contribute to the development of new anticoagulant therapies aimed at reducing the risk of these life-threatening events.In conclusion, thromboplastin is a fundamental element in the process of blood coagulation, serving as a catalyst that triggers the entire cascade necessary for clot formation. Its significance in both diagnostic and therapeutic applications highlights the need for continued research and understanding in this area. By comprehending the intricacies of thromboplastin and its role in hemostasis, healthcare professionals can better manage bleeding disorders and prevent thromboembolic events, ultimately improving patient outcomes. As we advance in medical science, the study of thromboplastin will undoubtedly remain a focal point in our quest to understand and treat coagulation disorders effectively.

在医学科学领域，理解血液凝固的组成部分对各种疾病的诊断和治疗至关重要。其中一个重要组成部分是组织纤维蛋白原，它在凝血过程中发挥着关键作用。组织纤维蛋白原是一种蛋白质复合物，它启动凝血级联反应，最终导致血块的形成。这个过程对于防止受伤时大量出血是至关重要的。当我们谈论组织纤维蛋白原时，通常指的是它的两种主要形式：组织因子（TF）和血小板因子3（PF3）。组织因子由受损组织释放，并与血液中的第七因子相互作用，使其活化为第七因子a。这个活化形式然后催化第十因子的转化为Xa，这是凝血共同途径中的关键步骤。另一方面，激活的血小板释放的血小板因子3为其他凝血因子的组装和有效工作提供了表面。组织纤维蛋白原的重要性不仅限于其在止血中的作用；它在各种临床环境中的意义也不容忽视。例如，在实验室测试中，如凝血酶原时间（PT）和活化部分凝血酶时间（aPTT），组织纤维蛋白原用于评估凝血途径的功能。测试结果异常可能表明潜在的疾病，如肝病、维生素K缺乏或体内抗凝剂的存在。此外，组织纤维蛋白原在治疗背景下的使用也不能被忽视。在某些情况下，患者可能需要给予凝血因子以管理诸如血友病等出血性疾病。理解组织纤维蛋白原如何与凝血级联的其他组成部分相互作用，可以帮助医疗提供者就治疗方案做出明智的决定。近年来，研究还集中在组织纤维蛋白原在更复杂的疾病如血栓栓塞中的作用。不当激活凝血级联反应可能导致血块的形成，阻塞血流，从而导致中风或心脏病发作等严重并发症。因此，研究组织纤维蛋白原及其机制可以有助于开发新的抗凝疗法，以降低这些危及生命事件的风险。总之，组织纤维蛋白原是血液凝固过程中一个基本要素，充当触发整个凝血形成所需级联反应的催化剂。它在诊断和治疗应用中的重要性突显了在这一领域继续研究和理解的必要性。通过理解组织纤维蛋白原及其在止血中的作用，医疗专业人员可以更好地管理出血性疾病并预防血栓栓塞事件，最终改善患者的结果。随着我们在医学科学上的进步，组织纤维蛋白原的研究无疑将继续成为我们有效理解和治疗凝血疾病的重点。