congenic

简明释义

英[kənˈdʒenɪk]美[kənˈdʒenɪk]

同类系的

英英释义

单词用法

同义词

反义词

例句

1.The result indicated that the genetic construction of congenic inbred strains was similar with the parents through more than the 20th generation back cross mating except for destination gene.

结果表明，经20代以上的回交，除目的基因外，均为轮回亲本的遗传组成。

2.The result indicated that the genetic construction of congenic inbred strains was similar with the parents through more than the 20th generation back cross mating except for destination gene.

结果表明，经20代以上的回交，除目的基因外，均为轮回亲本的遗传组成。

3.The congenic 同基因的 rats were bred to isolate the effects of a single genetic variation.

这些同基因的大鼠是为了隔离单一基因变异的影响而繁殖的。

4.Using congenic 同基因的 models can help clarify the role of specific genes in disease.

使用同基因的模型可以帮助阐明特定基因在疾病中的作用。

5.The study involved creating a congenic 同基因的 line to investigate metabolic disorders.

这项研究涉及创建一个同基因的品系以调查代谢紊乱。

6.The researchers used a congenic 同基因的 strain of mice to study the effects of a specific gene.

研究人员使用了一种同基因的小鼠品系来研究特定基因的影响。

7.In their experiments, they compared the congenic 同基因的 group with the wild-type group to see the differences in phenotype.

在实验中，他们将同基因的组与野生型组进行比较，以观察表型的差异。

作文

In the realm of genetics, the term congenic refers to organisms that are genetically identical except for a specific region of their genome. This concept is particularly important in the study of traits and diseases, as it allows researchers to isolate the effects of particular genes. For example, if scientists want to understand how a certain gene contributes to a disease, they can create congenic strains of mice where only the gene of interest differs between them. This way, they can observe the impact of that single gene in a controlled environment, minimizing the influence of other genetic variations.The development of congenic models has revolutionized biomedical research. By using these models, researchers can conduct experiments that lead to more accurate conclusions about gene function and its association with various phenotypes. For instance, a study involving congenic mice might reveal that a particular gene is responsible for susceptibility to a certain type of cancer. This knowledge can pave the way for targeted therapies and personalized medicine approaches, making treatments more effective.Moreover, congenic strains are also valuable in the field of behavioral genetics. Researchers can investigate how specific genes influence behavior by comparing congenic mice with different genetic backgrounds. This can help elucidate the genetic basis of complex behaviors such as aggression, anxiety, and social interactions. Understanding these genetic influences is crucial for developing interventions for psychological disorders.In agriculture, congenic plants and animals can be used to enhance desirable traits. For instance, a farmer may want to develop a crop that is resistant to a particular pest. By creating congenic lines that carry the resistance gene while keeping the rest of the genome unchanged, breeders can produce plants that are more resilient without sacrificing other valuable characteristics such as yield or taste.Despite the advantages, the use of congenic organisms also raises ethical questions. The manipulation of genomes to create these strains must be done responsibly, ensuring that animal welfare is prioritized. Furthermore, as we learn more about the complexities of genetics, it becomes evident that traits are often influenced by multiple genes and environmental factors. Thus, while congenic models provide significant insights, researchers must remain cautious about overgeneralizing their findings.In conclusion, the concept of congenic organisms plays a pivotal role in advancing our understanding of genetics. Whether in medical research, behavioral studies, or agricultural improvements, congenic models offer a powerful tool for isolating and studying the effects of specific genes. As science continues to evolve, the importance of these models will undoubtedly grow, leading to breakthroughs that could transform how we approach health and agriculture. However, with this power comes the responsibility to conduct research ethically and thoughtfully, ensuring that the benefits of our discoveries are realized without compromising the well-being of living organisms.

在遗传学领域，术语congenic指的是基因组中只有特定区域不同的基因相同的生物体。这个概念在研究性状和疾病时尤为重要，因为它使研究人员能够分离特定基因的影响。例如，如果科学家想要了解某个基因如何导致疾病，他们可以创建congenic小鼠，其中只有感兴趣的基因在它们之间有所不同。通过这种方式，他们可以在受控环境中观察单一基因的影响，最小化其他遗传变异的影响。congenic模型的发展彻底改变了生物医学研究。通过使用这些模型，研究人员可以进行实验，从而得出关于基因功能及其与各种表型相关性的更准确结论。例如，涉及congenic小鼠的研究可能会揭示某个特定基因负责对某种癌症的易感性。这一知识可以为靶向疗法和个性化医学方法铺平道路，使治疗更加有效。此外，congenic品系在行为遗传学领域也非常有价值。研究人员可以通过比较具有不同遗传背景的congenic小鼠来研究特定基因如何影响行为。这有助于阐明复杂行为的遗传基础，例如攻击性、焦虑和社会互动。理解这些遗传影响对于开发心理疾病的干预措施至关重要。在农业中，congenic植物和动物可以用于增强有利特性。例如，农民可能希望开发一种对特定害虫具有抗性的作物。通过创建携带抗性基因的congenic品系，同时保持其余基因组不变，育种者可以生产出更具韧性的植物，而不牺牲产量或口味等其他宝贵特性。尽管有这些优势，使用congenic生物体也引发了伦理问题。创建这些品系的基因组操控必须负责任地进行，确保动物福利优先。此外，随着我们对遗传学复杂性的了解加深，显而易见，性状通常受到多个基因和环境因素的影响。因此，尽管congenic模型提供了重要的见解，研究人员在推广他们的发现时仍然必须保持谨慎。总之，congenic生物体的概念在促进我们对遗传学的理解方面发挥着关键作用。无论是在医学研究、行为研究还是农业改进中，congenic模型都为分离和研究特定基因的影响提供了强大的工具。随着科学的不断发展，这些模型的重要性无疑会增加，从而导致可能改变我们对健康和农业的看法的突破。然而，伴随这种力量而来的责任是以伦理和深思熟虑的方式进行研究，确保我们发现的好处在不损害生物体福祉的情况下实现。