teratogenesis

简明释义

英[ˌterətəˈdʒenəsɪs]美[ˌterətəˈdʒenəsɪs]

n. 畸形生长；[胚] 畸形发生

英英释义

单词用法

同义词

反义词

例句

1.Objective To study the effect of methylmercury on the behavioral teratogenesis in filial rats.

目的为研究氯化甲基汞的染毒大鼠对其后代的行为致畸作用。

2.The time effect relationship between positional transfered novel gene (HCY 2) and neural tube teratogenesis, and their possible mechanisms were studied.

本文旨在研究定位转新基因(HCY -2)与神经管畸形发生的时间-效应关系及可能的作用机理。

3.To study the effect of the secondary metabolites of Rhizotonia Leguminicola on behavioral teratogenesis in mice.

研究了豆类丝核菌次级代谢产物对小鼠后代的行为致畸作用。

4.The time effect relationship between positional transfered novel gene (HCY 2) and neural tube teratogenesis, and their possible mechanisms were studied.

本文旨在研究定位转新基因(HCY -2)与神经管畸形发生的时间-效应关系及可能的作用机理。

5.Conclusion the methylmercury likely has the effect on behavioral teratogenesis of rats.

结论氯化甲基汞具有行为致畸作用。

6.Certain infections during pregnancy are linked to increased rates of teratogenesis.

怀孕期间某些感染与增加的畸形发生率有关。

7.The study of teratogenesis helps scientists identify potential risks in prenatal care.

对畸形发生的研究帮助科学家识别产前护理中的潜在风险。

8.Environmental factors can play a significant role in teratogenesis during fetal development.

环境因素在胎儿发育过程中可能对畸形发生产生重大影响。

9.Understanding the mechanisms of teratogenesis is crucial for developing safer medications for pregnant women.

理解畸形发生的机制对于为孕妇开发更安全的药物至关重要。

10.Research on teratogenesis has revealed how certain drugs can lead to birth defects.

对畸形发生的研究揭示了某些药物如何导致出生缺陷。

作文

Teratogenesis is a fascinating yet complex process that refers to the development of congenital malformations or birth defects in an embryo or fetus. The term itself derives from the Greek words 'teras,' meaning monster, and 'genes,' meaning born of or produced by. Understanding teratogenesis is crucial for medical professionals, especially those working in obstetrics and pediatrics, as it directly impacts the health of future generations. During the early stages of pregnancy, an embryo undergoes rapid development, and various factors can influence this process. These factors include genetic predispositions, environmental exposures, and maternal health. For instance, exposure to certain medications, alcohol, or infectious agents during pregnancy can lead to teratogenesis. One well-known example is fetal alcohol syndrome, which results from excessive alcohol consumption by the mother during pregnancy, leading to physical and cognitive impairments in the child. Moreover, the timing of exposure to teratogenic agents is critical. The first trimester is particularly sensitive since this is when the major organs and systems are forming. If a teratogen is introduced during this period, it can disrupt normal development and result in severe defects. For instance, the drug thalidomide, which was prescribed in the late 1950s and early 1960s for morning sickness, is infamous for causing limb deformities in babies when taken during the first trimester. This tragedy highlighted the importance of understanding teratogenesis and led to stricter regulations regarding medication use during pregnancy. In addition to pharmaceutical agents, other environmental factors can also contribute to teratogenesis. For example, exposure to high levels of radiation, certain chemicals, and infections such as rubella can lead to significant birth defects. The Zika virus outbreak in recent years further underscored the importance of awareness surrounding teratogenesis, as it was linked to microcephaly and other severe developmental issues in infants born to infected mothers. Preventing teratogenesis requires a multi-faceted approach, including education and awareness among expectant mothers about potential risks. Healthcare providers play a vital role in advising women of childbearing age on the importance of maintaining a healthy lifestyle, avoiding harmful substances, and seeking prenatal care. Additionally, public health initiatives aimed at reducing exposure to known teratogens can significantly improve maternal and fetal health outcomes. Research into teratogenesis continues to evolve, with scientists exploring the genetic and molecular mechanisms behind these developmental anomalies. Advances in technology, such as genetic screening and improved imaging techniques, allow for earlier detection and intervention, which can mitigate some of the impacts of teratogenic exposures. In conclusion, teratogenesis is a critical area of study that encompasses a wide range of factors affecting embryonic development. By understanding the causes and consequences of teratogenic events, we can better protect the health of future generations. It is essential for both healthcare professionals and the general public to remain informed about the risks associated with teratogenesis, fostering a healthier environment for mothers and their children.

畸形发生是一个迷人而复杂的过程，指的是胚胎或胎儿先天性畸形或出生缺陷的发展。这个术语本身源于希腊词“teras”，意为怪物，以及“genes”，意为由……产生或生育。理解teratogenesis对医疗专业人员至关重要，尤其是那些从事产科和儿科的专业人员，因为它直接影响到未来几代人的健康。在怀孕的早期阶段，胚胎经历快速的发展，各种因素可以影响这一过程。这些因素包括遗传倾向、环境暴露和母体健康。例如，在怀孕期间接触某些药物、酒精或感染性病原体可能导致teratogenesis。一个众所周知的例子是胎儿酒精综合症，它是由于母亲在怀孕期间过量饮酒而导致的，导致孩子在身体和认知方面的障碍。此外，接触畸形发生因子的时机也至关重要。第一孕期特别敏感，因为这是主要器官和系统形成的时期。如果在此期间接触到畸形因子，可能会干扰正常发育并导致严重缺陷。例如，药物沙利度胺在20世纪50年代末和60年代初被开给孕妇用于缓解晨吐，但在第一孕期服用时以导致婴儿肢体畸形而臭名昭著。这场悲剧突显了理解teratogenesis的重要性，并导致了对孕期药物使用的更严格监管。除了药物因素，其他环境因素也可能导致teratogenesis。例如，暴露于高水平的辐射、某些化学物质和感染（如风疹）都可能导致重大出生缺陷。近年来，寨卡病毒疫情进一步强调了对teratogenesis的关注，因为它与感染母亲所生婴儿的小头畸形和其他严重发育问题有关。预防teratogenesis需要多方面的方法，包括提高对潜在风险的认知和教育。医疗提供者在建议育龄女性保持健康生活方式、避免有害物质以及寻求产前护理方面发挥着至关重要的作用。此外，旨在减少已知畸形因子暴露的公共卫生倡议可以显著改善母婴健康结果。对teratogenesis的研究持续发展，科学家们正在探索这些发育异常背后的遗传和分子机制。技术的进步，如基因筛查和改进的成像技术，使得早期检测和干预成为可能，从而减轻一些畸形暴露的影响。总之，teratogenesis是一个涵盖多种影响胚胎发育因素的关键研究领域。通过理解畸形事件的原因和后果，我们可以更好地保护未来几代人的健康。医疗专业人员和公众都应保持对teratogenesis相关风险的认识，为母亲和孩子营造一个更健康的环境。