chronic toxicity test

简明释义

慢性毒性检验

英英释义

例句

1.The chronic toxicity test was part of the preclinical trials for the new vaccine.

该慢性毒性测试是新疫苗临床前试验的一部分。

2.The researchers conducted a chronic toxicity test to evaluate the long-term effects of the new drug on rats.

研究人员进行了慢性毒性测试以评估新药对老鼠的长期影响。

3.The results of the chronic toxicity test indicated that prolonged exposure could lead to serious health issues.

该慢性毒性测试的结果表明，长期接触可能导致严重的健康问题。

4.Regulatory agencies often require a chronic toxicity test for any new pesticide before approval.

监管机构通常要求在批准任何新农药之前进行慢性毒性测试。

5.Before releasing the chemical into the market, the company needed to complete a chronic toxicity test to ensure safety.

在将化学品投放市场之前，公司需要完成慢性毒性测试以确保安全。

作文

In the realm of toxicology, understanding the effects of substances on living organisms is crucial for ensuring safety and health. One important aspect of this field is the assessment of long-term exposure to chemicals, which is often evaluated through a procedure known as a chronic toxicity test. A chronic toxicity test is designed to determine the adverse effects that may arise from prolonged exposure to a substance, typically over a period of several weeks or months. This type of testing is essential for various industries, including pharmaceuticals, agriculture, and environmental science, where substances must be evaluated for their potential risks before they can be approved for use.The significance of conducting a chronic toxicity test cannot be overstated. Many substances may not exhibit immediate harmful effects, but long-term exposure could lead to serious health issues such as cancer, organ damage, or reproductive problems. For instance, in the pharmaceutical industry, new drugs undergo rigorous testing to ensure that they do not cause chronic health problems in patients. Similarly, agricultural chemicals must be assessed to ensure that they do not pose long-term risks to humans, animals, or ecosystems.A typical chronic toxicity test involves administering a specific dose of a chemical to test subjects, usually laboratory animals, over an extended period. Researchers monitor the subjects for any signs of adverse effects, including changes in behavior, weight loss, or physiological abnormalities. Blood tests and other diagnostic measures are often employed to gather comprehensive data on the health status of the subjects. The results of these tests help scientists understand the safe levels of exposure and the potential risks associated with the substance.Moreover, regulatory agencies, such as the Environmental Protection Agency (EPA) in the United States, rely heavily on data from chronic toxicity tests when establishing guidelines and safety limits for chemical exposure. These regulations are vital for protecting public health and the environment, as they help prevent the release of harmful substances into the market without proper evaluation.In addition to its importance in regulatory frameworks, the chronic toxicity test also plays a role in scientific research. By understanding how different substances interact with biological systems over time, researchers can develop safer alternatives and improve existing products. This knowledge contributes to advancements in medicine, agriculture, and environmental protection, ultimately benefiting society as a whole.However, it is essential to note that chronic toxicity tests can also raise ethical questions regarding the use of animals in research. As society becomes increasingly aware of animal welfare issues, there is a growing demand for alternative testing methods that do not involve live subjects. Scientists are exploring various approaches, including in vitro testing and computer modeling, to reduce the reliance on animal testing while still obtaining accurate data on chronic toxicity.In conclusion, the chronic toxicity test is a vital tool in toxicology that helps assess the long-term effects of chemical exposure on living organisms. Its applications span across multiple industries, ensuring that substances are safe for human use and environmental health. While ethical considerations surrounding animal testing continue to evolve, the importance of chronic toxicity tests in safeguarding public health remains clear. As research progresses, it is hoped that more humane and effective testing methods will emerge, further enhancing our understanding of chronic toxicity and its implications for society.

在毒理学领域，了解物质对生物体的影响对于确保安全和健康至关重要。这个领域的一个重要方面是评估化学物质的长期暴露，这通常通过一种称为慢性毒性测试的程序来进行。慢性毒性测试旨在确定由于长期接触某种物质而可能产生的不良影响，通常持续数周或数月。这种类型的测试对于制药、农业和环境科学等多个行业至关重要，因为在这些行业中，必须在批准使用之前评估物质的潜在风险。进行慢性毒性测试的重要性不容小觑。许多物质可能不会表现出立即的有害影响，但长期暴露可能导致严重的健康问题，如癌症、器官损伤或生殖问题。例如，在制药行业，新药物经过严格测试，以确保它们不会在患者身上引起慢性健康问题。同样，农业化学品也必须评估，以确保它们不会对人类、动物或生态系统造成长期风险。典型的慢性毒性测试涉及在较长时间内向实验对象（通常是实验室动物）施加特定剂量的化学物质。研究人员监测实验对象是否出现任何不良影响的迹象，包括行为变化、体重减轻或生理异常。通常会进行血液测试和其他诊断措施，以收集有关实验对象健康状况的全面数据。这些测试的结果帮助科学家了解安全的暴露水平以及与该物质相关的潜在风险。此外，像美国环境保护局（EPA）这样的监管机构在建立化学物质暴露的指导方针和安全限值时，严重依赖于慢性毒性测试的数据。这些法规对于保护公众健康和环境至关重要，因为它们有助于防止在没有适当评估的情况下将有害物质投放市场。除了在监管框架中的重要性外，慢性毒性测试还在科学研究中发挥着作用。通过了解不同物质如何在一段时间内与生物系统相互作用，研究人员可以开发更安全的替代品并改善现有产品。这些知识有助于医学、农业和环境保护的进步，最终使整个社会受益。然而，需要注意的是，慢性毒性测试也可能引发关于动物研究使用的伦理问题。随着社会对动物福利问题的日益关注，人们对不涉及活体实验对象的替代测试方法的需求日益增加。科学家们正在探索各种方法，包括体外测试和计算机建模，以减少对动物测试的依赖，同时仍能获得准确的慢性毒性数据。总之，慢性毒性测试是毒理学中的一个重要工具，有助于评估化学物质对生物体的长期影响。其应用跨越多个行业，确保物质对人类使用和环境健康是安全的。尽管围绕动物测试的伦理考虑持续演变，但慢性毒性测试在保护公众健康方面的重要性依然清晰。随着研究的进展，希望能出现更人道和有效的测试方法，进一步增强我们对慢性毒性及其对社会影响的理解。