abortive infection

简明释义

顿挫性感染

英英释义

例句

1.The patient experienced an abortive infection, indicating that the virus was present but did not cause any significant symptoms.

患者经历了一次abortive infection，这表明病毒存在但没有引起任何显著症状。

2.In some cases, an abortive infection can lead to immunity without the individual ever knowing they were infected.

在某些情况下，abortive infection可以在个体未意识到感染的情况下导致免疫力。

3.An abortive infection occurs when a pathogen enters the body but fails to replicate effectively.

当病原体进入体内但无法有效复制时，就会发生abortive infection。

4.Researchers are studying how abortive infections can provide insights into vaccine development.

研究人员正在研究如何通过abortive infections为疫苗开发提供见解。

5.Understanding the mechanisms behind abortive infections could help in creating better antiviral therapies.

理解abortive infections背后的机制可能有助于开发更好的抗病毒疗法。

作文

In the field of virology, the term abortive infection refers to a type of viral infection that fails to produce new infectious virions. This phenomenon occurs when a virus enters a host cell but does not successfully replicate or spread throughout the organism. Understanding the mechanisms behind abortive infection is crucial for developing effective antiviral strategies and therapeutic interventions. When a virus infects a host cell, it typically hijacks the cellular machinery to produce copies of itself. However, in an abortive infection, the virus may encounter obstacles that prevent this replication process. These obstacles can include the activation of the host's immune response, the presence of antiviral drugs, or inherent limitations in the virus's ability to exploit the host's cellular functions. As a result, while the virus may enter the cell, it ultimately fails to propagate, leading to a situation where the infection is effectively 'aborted.' One of the significant implications of abortive infection is its potential role in shaping viral evolution. When a virus experiences repeated instances of abortive infections, it may adapt by evolving new strategies to evade the host's defenses or improve its replication efficiency. This evolutionary pressure can lead to the emergence of more virulent strains, complicating efforts to control viral outbreaks. Therefore, studying abortive infection not only enhances our understanding of viral biology but also informs public health strategies aimed at managing viral diseases. Furthermore, abortive infection can have important clinical implications. For instance, in some cases, a patient may exhibit symptoms of a viral infection without the presence of infectious particles in their bloodstream due to an abortive infection. This can lead to challenges in diagnosing and treating viral illnesses, as traditional methods may fail to detect the virus despite the patient's symptoms. Clinicians must be aware of the possibility of abortive infection when evaluating patients, especially in cases where standard diagnostic tests yield negative results. In conclusion, the concept of abortive infection is a vital aspect of virology that highlights the complexities of viral-host interactions. By recognizing the factors that contribute to abortive infections, researchers and healthcare professionals can better understand viral pathogenesis and develop targeted therapies to combat viral diseases. The ongoing study of abortive infection will undoubtedly continue to provide valuable insights into the intricate dynamics of viral infections and their impact on human health.

在病毒学领域，术语abortive infection指的是一种病毒感染类型，该类型未能产生新的传染性病毒粒子。这种现象发生在病毒进入宿主细胞但未能成功复制或传播至整个生物体时。理解abortive infection背后的机制对于开发有效的抗病毒策略和治疗干预至关重要。当病毒感染宿主细胞时，它通常会劫持细胞的机制来生产自己的副本。然而，在abortive infection中，病毒可能会遇到阻碍，阻止这一复制过程。这些障碍可以包括宿主免疫反应的激活、抗病毒药物的存在，或者病毒利用宿主细胞功能的固有限制。因此，尽管病毒可能进入细胞，但最终未能繁殖，导致感染有效地“中止”。abortive infection的一个重要影响是其在塑造病毒进化中的潜在作用。当病毒经历重复的中止感染实例时，它可能通过进化出新的策略来逃避宿主的防御或提高其复制效率而适应。这种进化压力可能导致更具致病性的菌株的出现，复杂化了控制病毒爆发的努力。因此，研究abortive infection不仅增强了我们对病毒生物学的理解，还为旨在管理病毒疾病的公共卫生策略提供了信息。此外，abortive infection可能具有重要的临床意义。例如，在某些情况下，患者可能表现出病毒感染的症状，但由于中止感染，血液中没有传染性粒子的存在。这可能导致在诊断和治疗病毒疾病时面临挑战，因为传统方法可能无法检测到病毒，尽管患者有症状。在评估患者时，临床医生必须意识到abortive infection的可能性，特别是在常规诊断测试结果为阴性时。总之，abortive infection的概念是病毒学的一个重要方面，突显了病毒与宿主相互作用的复杂性。通过认识到导致中止感染的因素，研究人员和医疗专业人员可以更好地理解病毒致病机制，并开发针对性的疗法来对抗病毒疾病。对abortive infection的持续研究无疑将继续提供有关病毒感染复杂动态及其对人类健康影响的宝贵见解。