thymidine kinase

简明释义

胸苷激酶

英英释义

例句

1.The activity of thymidine kinase is often measured in clinical diagnostics.

在临床诊断中，通常会测量胸苷激酶的活性。

2.Mutations in the gene coding for thymidine kinase can lead to genetic disorders.

编码胸苷激酶的基因突变可能导致遗传疾病。

3.In cancer therapy, thymidine kinase can be used as a target for drug development.

在癌症治疗中，胸苷激酶可以作为药物开发的靶点。

4.Researchers are studying the role of thymidine kinase in viral infections.

研究人员正在研究胸苷激酶在病毒感染中的作用。

5.The enzyme thymidine kinase is crucial for DNA synthesis.

酶胸苷激酶对DNA合成至关重要。

作文

Thymidine kinase is an essential enzyme that plays a critical role in the synthesis of DNA. It catalyzes the phosphorylation of thymidine, a nucleoside that is a building block of DNA. This process is vital for cell division and proliferation, as it ensures that cells have the necessary components to replicate their genetic material. In many organisms, including humans, thymidine kinase (胸苷激酶) is particularly important during the S-phase of the cell cycle, where DNA synthesis takes place. Without adequate levels of this enzyme, cells may not be able to divide properly, leading to various health issues, including cancer.The importance of thymidine kinase (胸苷激酶) extends beyond normal cellular function. It has been studied extensively in the context of viral infections, especially those caused by herpesviruses. These viruses often encode their own version of thymidine kinase (胸苷激酶), which can be targeted by antiviral drugs. For instance, the drug acyclovir is a well-known treatment for herpes simplex virus infections; it specifically targets the viral thymidine kinase (胸苷激酶) to inhibit viral replication. This highlights the enzyme's role not only in cellular biology but also in therapeutic applications.Research has shown that measuring the levels of thymidine kinase (胸苷激酶) in the blood can provide valuable information regarding the presence of certain diseases. Elevated levels of this enzyme are often associated with increased cellular turnover, which is commonly seen in cancer patients. Therefore, thymidine kinase (胸苷激酶) is used as a biomarker in clinical settings to monitor disease progression and response to treatment.In addition to its clinical significance, thymidine kinase (胸苷激酶) is also a subject of interest in research laboratories. Scientists are investigating ways to manipulate this enzyme to enhance gene therapy techniques. By using modified versions of thymidine kinase (胸苷激酶), researchers aim to create targeted therapies that can deliver genes to specific cells, potentially offering cures for genetic disorders.In conclusion, thymidine kinase (胸苷激酶) is a pivotal enzyme with far-reaching implications in both normal cellular functions and medical research. Its role in DNA synthesis makes it indispensable for cell division, while its involvement in viral infections and cancer diagnostics underscores its importance in healthcare. As research continues to evolve, the understanding and application of thymidine kinase (胸苷激酶) will likely expand, paving the way for novel therapeutic strategies and better diagnostic tools.

胸苷激酶是一种重要的酶，在DNA合成中发挥着关键作用。它催化胸苷的磷酸化，胸苷是一种核苷，是DNA的构建块。这个过程对细胞分裂和增殖至关重要，因为它确保细胞拥有复制遗传物质所需的成分。在许多生物体中，包括人类，胸苷激酶在细胞周期的S期中尤为重要，此时DNA合成发生。如果没有足够水平的这种酶，细胞可能无法正常分裂，导致各种健康问题，包括癌症。胸苷激酶的重要性不仅限于正常细胞功能。它在病毒感染的背景下得到了广泛研究，尤其是那些由疱疹病毒引起的病毒。这些病毒通常编码它们自己的胸苷激酶，可以被抗病毒药物靶向。例如，阿昔洛韦是一种治疗单纯疱疹病毒感染的知名药物；它专门针对病毒胸苷激酶以抑制病毒复制。这突显了该酶在细胞生物学和治疗应用中的作用。研究表明，测量血液中胸苷激酶的水平可以提供有关某些疾病存在的有价值信息。该酶的升高水平常与细胞周转增加相关，这在癌症患者中常见。因此，胸苷激酶作为生物标志物在临床环境中用于监测疾病进展和治疗反应。除了其临床意义外，胸苷激酶也是研究实验室中的一个研究对象。科学家们正在研究操纵这种酶的方法，以增强基因治疗技术。通过使用改造版的胸苷激酶，研究人员旨在创造可以将基因传递到特定细胞的靶向疗法，可能为遗传疾病提供治愈方案。总之，胸苷激酶是一种关键酶，在正常细胞功能和医学研究中具有深远的影响。它在DNA合成中的作用使其对细胞分裂不可或缺，而它在病毒感染和癌症诊断中的参与则强调了其在医疗保健中的重要性。随着研究的不断发展，对胸苷激酶的理解和应用可能会扩大，为新型治疗策略和更好的诊断工具铺平道路。