adriamycin

简明释义

英[ˌeɪdrɪəˈmaɪsɪn]美[ˌedriəˈmaɪsən]

n. [微] 阿霉素，[药] 亚德里亚霉素

英英释义

单词用法

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例句

1.Conclusion: Integrated backscatter parameters was of value in the assessment of adriamycin-induced cardiomyopathy.

结论：心肌背向散射积分参数可有效评价阿霉素诱导兔心肌病模型的建立。

2.Conclusion Myocardial contraction function was reduced in adriamycin-induced rabbit model of dilated cardiomyopathy.

结论在阿霉素所致兔心肌病模型中心肌收缩功能降低。

3.Losartan can reduce kidney lesions in adriamycin-induced nephropathy in rats.

推测氯沙坦能减轻阿霉素肾病大鼠的肾脏损害。

4.These results will be useful for further understanding the interaction of DNA with adriamycin.

这些结果为深入理解阿霉素与DNA的相互作用提供了帮助。

5.The chemotherapeutics which inhibition rate was more than 50% were mitomycin, 5-FU, and Adriamycin.

达到50%以上抑制率的药物只有丝裂霉素、5氟尿嘧啶、阿霉素。

6.Objective: To evaluate the efficacy and safety of adriamycin injection and adriamycin vial for injection.

目的：评价水剂阿霉素与粉剂阿霉素在临床疗效和安全性方面的差异。

7.Research shows that adriamycin can effectively target certain types of cancer cells.

研究表明，阿霉素可以有效靶向某些类型的癌细胞。

8.Patients receiving adriamycin should be monitored for cardiac function.

接受阿霉素治疗的患者应监测心脏功能。

9.The oncologist explained how adriamycin works in the body to fight cancer.

肿瘤科医生解释了阿霉素在体内如何抗击癌症。

10.Side effects of adriamycin may include nausea and hair loss.

阿霉素的副作用可能包括恶心和脱发。

11.The doctor prescribed adriamycin for the patient's chemotherapy treatment.

医生为患者的化疗治疗开了阿霉素。

作文

Adriamycin, known scientifically as doxorubicin, is a powerful chemotherapeutic agent that has been widely used in the treatment of various types of cancer. This drug belongs to a class of medications called anthracyclines and is derived from the bacterium Streptomyces peucetius. The discovery of adriamycin has significantly advanced the field of oncology, providing hope for many patients battling malignancies such as breast cancer, leukemia, and lymphoma.The mechanism of action of adriamycin involves intercalation into DNA strands, which disrupts the replication process of cancer cells. By inserting itself between the base pairs of DNA, adriamycin inhibits the enzyme topoisomerase II, preventing the cancer cells from dividing and proliferating. This targeted approach makes adriamycin particularly effective against rapidly dividing cells, which is a hallmark of cancerous growth.Despite its effectiveness, the use of adriamycin is not without side effects. Patients undergoing treatment may experience a range of adverse reactions, including nausea, vomiting, hair loss, and fatigue. One of the most concerning side effects is cardiotoxicity, which can lead to long-term heart damage. Therefore, it is crucial for healthcare providers to monitor patients closely during treatment with adriamycin and manage any potential complications.In clinical settings, adriamycin is often used in combination with other chemotherapy agents to enhance its efficacy. This combination therapy can improve treatment outcomes and reduce the chances of drug resistance. For instance, when used alongside cyclophosphamide and fluorouracil, adriamycin has shown remarkable success in treating early-stage breast cancer.Research continues to explore new ways to optimize the use of adriamycin and minimize its side effects. Scientists are investigating targeted delivery systems that can direct the drug specifically to cancer cells, thereby reducing exposure to healthy tissues. Additionally, studies are underway to identify biomarkers that could predict which patients are more likely to benefit from adriamycin therapy.Overall, adriamycin remains a cornerstone in the arsenal against cancer. Its ability to effectively combat various malignancies has made it an essential component of many chemotherapy regimens. As research progresses, the hope is to refine its application, making treatment safer and more effective for patients. The journey of adriamycin from discovery to clinical use exemplifies the ongoing battle against cancer and the relentless pursuit of better therapeutic options for those affected by this disease.

阿霉素，科学上称为多柔比星，是一种强效的化疗药物，广泛用于治疗各种类型的癌症。这种药物属于一种称为蒽环类药物的药物类别，来源于细菌Streptomyces peucetius。阿霉素的发现显著推动了肿瘤学领域的发展，为许多与恶性肿瘤作斗争的患者带来了希望。阿霉素的作用机制涉及插入DNA链中，破坏癌细胞的复制过程。通过将自身插入DNA的碱基对之间，阿霉素抑制酶拓扑异构酶II，阻止癌细胞的分裂和增殖。这种靶向方法使得阿霉素在快速分裂的细胞中尤其有效，这是癌症生长的一个标志。尽管有效，使用阿霉素并非没有副作用。接受治疗的患者可能会经历一系列不良反应，包括恶心、呕吐、脱发和疲劳。其中最令人担忧的副作用是心脏毒性，这可能导致长期的心脏损伤。因此，医疗提供者在使用阿霉素治疗期间密切监测患者并管理任何潜在的并发症至关重要。在临床环境中，阿霉素通常与其他化疗药物联合使用，以增强其疗效。这种联合治疗可以改善治疗效果，并减少药物耐药的机会。例如，当与环磷酰胺和氟尿嘧啶联合使用时，阿霉素在治疗早期乳腺癌方面显示出显著成功。研究仍在继续探索优化使用阿霉素和最小化其副作用的新方法。科学家们正在研究靶向递送系统，可以将药物直接输送到癌细胞，从而减少对健康组织的暴露。此外，正在进行的研究旨在识别生物标志物，以预测哪些患者更有可能从阿霉素治疗中受益。总体而言，阿霉素仍然是抗击癌症的重要组成部分。它有效对抗各种恶性肿瘤的能力使其成为许多化疗方案的核心成分。随着研究的进展，希望能完善其应用，使治疗对患者更加安全和有效。阿霉素从发现到临床使用的历程，体现了与癌症的持续斗争以及对改善受此疾病影响的患者的治疗选择的不懈追求。