DNA microarray

简明释义

基因图谱

英英释义

A DNA microarray is a laboratory tool used to detect the expression of thousands of genes at the same time. It consists of a small solid surface onto which DNA molecules are attached in an orderly manner.

DNA微阵列是一种实验室工具,用于同时检测成千上万基因的表达。它由一个小的固体表面组成,DNA分子以有序的方式附着在其上。

例句

1.The DNA microarray technology allows for the simultaneous measurement of thousands of genes.

DNA微阵列技术允许同时测量成千上万的基因。

2.Researchers used a DNA microarray to analyze gene expression levels in cancer cells.

研究人员使用了DNA微阵列来分析癌细胞中的基因表达水平。

3.By utilizing a DNA microarray, scientists can identify genetic mutations associated with diseases.

通过利用DNA微阵列,科学家可以识别与疾病相关的基因突变。

4.The results from the DNA microarray experiment provided insights into the patient's genetic profile.

来自DNA微阵列实验的结果为患者的基因特征提供了见解。

5.A DNA microarray can help determine the effectiveness of a particular drug on different patients.

一个DNA微阵列可以帮助确定特定药物对不同患者的有效性。

作文

The field of genetics has made remarkable strides in recent decades, leading to significant advancements in our understanding of biological systems. One of the most revolutionary tools in this domain is the DNA microarray, a powerful technology that allows researchers to analyze thousands of genes simultaneously. This innovation has transformed the way we approach genetic research and has opened new avenues for medical diagnostics and treatments.A DNA microarray is essentially a chip that contains a grid of microscopic spots, each of which is coated with a specific DNA sequence. These sequences can correspond to genes from various organisms, including humans, plants, and bacteria. When a sample of DNA or RNA is applied to the chip, it will hybridize, or bind, to the complementary sequences present on the array. This process enables scientists to determine which genes are active in a particular sample, providing insights into gene expression patterns.The implications of using a DNA microarray are profound. For instance, in cancer research, scientists can compare the expression levels of genes in healthy tissue versus tumor tissue. By identifying which genes are overexpressed or underexpressed in cancer cells, researchers can gain insights into the mechanisms of cancer development and progression. This knowledge can lead to the identification of potential biomarkers for diagnosis and targets for new therapies.Moreover, the application of DNA microarray technology extends beyond cancer. It is utilized in various fields, including pharmacogenomics, which studies how genes affect a person's response to drugs. By analyzing gene expression profiles, healthcare providers can tailor medications to individual patients, minimizing adverse effects and maximizing therapeutic efficacy.Despite its advantages, the use of DNA microarray technology also presents challenges. The interpretation of the vast amounts of data generated can be complex, requiring sophisticated bioinformatics tools and expertise. Additionally, there are concerns regarding the reproducibility of results, as variations in experimental conditions can lead to different outcomes.In conclusion, the advent of the DNA microarray has significantly advanced our ability to study and understand genetic information. Its applications in cancer research, personalized medicine, and other areas of biology underscore its importance in modern science. As technology continues to evolve, it is likely that DNA microarray technology will become even more refined, paving the way for further discoveries that could revolutionize healthcare and our understanding of life itself.

遗传学领域在近几十年取得了显著进展,极大地推动了我们对生物系统的理解。其中最具革命性的一项工具就是DNA微阵列,这是一项强大的技术,允许研究人员同时分析成千上万的基因。这一创新改变了我们研究遗传学的方式,并为医学诊断和治疗开辟了新的途径。DNA微阵列本质上是一种芯片,包含一个微观点的网格,每个点上涂有特定的DNA序列。这些序列可以对应于各种生物体的基因,包括人类、植物和细菌。当将DNA或RNA样本应用到芯片上时,它将与阵列上存在的互补序列杂交或结合。这一过程使科学家能够确定特定样本中哪些基因是活跃的,从而提供基因表达模式的见解。使用DNA微阵列的意义深远。例如,在癌症研究中,科学家可以比较健康组织与肿瘤组织中基因的表达水平。通过识别在癌细胞中过度表达或低表达的基因,研究人员可以深入了解癌症发展的机制。这一知识可能导致潜在生物标志物的识别,用于诊断和新疗法的靶向。此外,DNA微阵列技术的应用不仅限于癌症。它还被用于药物基因组学,这一领域研究基因如何影响个人对药物的反应。通过分析基因表达谱,医疗服务提供者可以根据个体患者的情况量身定制药物,从而最小化不良反应并最大化治疗效果。尽管具有优势,使用DNA微阵列技术也面临挑战。生成的大量数据的解释可能很复杂,需要复杂的生物信息学工具和专业知识。此外,关于结果可重复性的担忧也存在,因为实验条件的变化可能导致不同的结果。总之,DNA微阵列的出现显著提高了我们研究和理解遗传信息的能力。它在癌症研究、个性化医学和其他生物学领域的应用突显了其在现代科学中的重要性。随着技术的不断发展,DNA微阵列技术可能会变得更加精细,为进一步的发现铺平道路,这些发现可能会彻底改变医疗保健和我们对生命本身的理解。

相关单词

microarray

microarray详解:怎么读、什么意思、用法