sulfadoxine

简明释义

英[sʌl.fəˈdɒk.siːn]美[sʌl.fəˈdɑk.saɪn]

n. 周效磺胺；磺胺多辛

英英释义

单词用法

同义词

反义词

例句

1.Until recently, the official treatment policy for malaria was sulfadoxine-pyrimethamine (sp). Chloroquine, however, is still widely used despite significant drug resistance.

直到最近，官方才采用了sulfadoxine -pyrimethamine (SP)的治疗方法，但氯喹的使用范围仍很广，尽管它有着很强的抗药性。

2.Resistance to earlier generation antimalarial medicines such as chloroquine and sulfadoxine-pyrimethamine is widespread in most malaria-endemic countries.

在大多数疟疾流行国家，对氯喹和磺胺多辛+乙胺嘧啶等较早一代抗疟药物的耐药性十分普遍。

3.This is the use of a single drug (or monotherapy) of chloroquine, sulfadoxine-pyrimethamine, or another antimalarial medicine to fight malaria.

这种疗法使用氯喹、磺胺多辛-乙胺嘧啶或另一种抗疟药物等单一药物治疗疟疾（亦称单一疗法）。

4.Until recently, the official treatment policy for malaria was sulfadoxine-pyrimethamine (sp). Chloroquine, however, is still widely used despite significant drug resistance.

直到最近，官方才采用了sulfadoxine -pyrimethamine (SP)的治疗方法，但氯喹的使用范围仍很广，尽管它有着很强的抗药性。

5.The doctor prescribed sulfadoxine to treat the patient's malaria infection.

医生开了sulfadoxine来治疗患者的疟疾感染。

6.In combination with pyrimethamine, sulfadoxine is used to enhance the effectiveness of malaria treatment.

与吡美莫司联合使用，sulfadoxine用于增强疟疾治疗的效果。

7.Clinical trials have shown that sulfadoxine can reduce the severity of symptoms in malaria patients.

临床试验表明，sulfadoxine可以减轻疟疾患者的症状严重程度。

8.Patients allergic to sulfa drugs should avoid taking sulfadoxine.

对磺胺药物过敏的患者应避免服用sulfadoxine。

9.The formulation of sulfadoxine is crucial for ensuring its stability in tablets.

确保sulfadoxine在药片中稳定性的配方至关重要。

作文

Sulfadoxine is a sulfonamide antibiotic that has been widely used in the treatment of various infections. It is particularly effective against certain types of bacterial infections and is often combined with pyrimethamine to treat malaria. This combination works by inhibiting the folic acid synthesis in the parasites, ultimately leading to their death. The use of sulfadoxine (磺胺嘧啶) has been crucial in regions where malaria is endemic, providing a means to combat this life-threatening disease. The history of sulfadoxine (磺胺嘧啶) dates back to the early 20th century when sulfonamides were first discovered. These drugs revolutionized the treatment of bacterial infections and paved the way for the development of other antibiotics. Sulfadoxine (磺胺嘧啶) was later identified as a potent agent against the protozoan parasite responsible for malaria, making it an essential component of antimalarial therapy. One of the significant advantages of using sulfadoxine (磺胺嘧啶) is its long half-life, which allows for once-weekly dosing in the treatment of malaria. This feature enhances patient compliance and makes it easier to administer in areas with limited healthcare resources. However, like all medications, sulfadoxine (磺胺嘧啶) is not without its side effects. Some patients may experience allergic reactions, skin rashes, or gastrointestinal disturbances. Therefore, it is vital for healthcare providers to monitor patients closely during treatment. In recent years, there has been growing concern about the emergence of drug-resistant strains of malaria parasites. This resistance can diminish the efficacy of sulfadoxine (磺胺嘧啶) and other antimalarial agents, making it increasingly challenging to control malaria outbreaks. Researchers are actively exploring alternative treatments and combination therapies to overcome this issue. Despite these challenges, sulfadoxine (磺胺嘧啶) remains a valuable tool in the fight against malaria. Its role in public health initiatives aimed at reducing the incidence of malaria cannot be overstated. In many countries, especially in Africa, sulfadoxine (磺胺嘧啶) is part of the standard treatment protocol for uncomplicated malaria. In conclusion, sulfadoxine (磺胺嘧啶) is a significant antibiotic that has played a crucial role in treating malaria and other bacterial infections. Its effectiveness, combined with its long half-life, makes it a practical choice in many clinical settings. However, the rise of drug resistance highlights the need for ongoing research and development of new therapeutic strategies. Understanding the role of sulfadoxine (磺胺嘧啶) in modern medicine is essential for both healthcare professionals and patients alike, as it continues to be an important weapon in the global fight against infectious diseases.

磺胺嘧啶是一种广泛用于治疗各种感染的磺胺类抗生素。它对某些类型的细菌感染特别有效，通常与吡美莫司联合使用以治疗疟疾。这种组合通过抑制寄生虫的叶酸合成，最终导致其死亡。sulfadoxine（磺胺嘧啶）的使用在疟疾流行地区至关重要，为抗击这种危及生命的疾病提供了手段。sulfadoxine（磺胺嘧啶）的历史可以追溯到20世纪初，当时首次发现了磺胺类药物。这些药物彻底改变了细菌感染的治疗，并为其他抗生素的发展铺平了道路。后来，sulfadoxine（磺胺嘧啶）被确定为对负责疟疾的原生动物寄生虫的有效药物，使其成为抗疟疾治疗的重要组成部分。使用sulfadoxine（磺胺嘧啶）的一个显著优点是其较长的半衰期，这使得在疟疾治疗中可以每周一次给药。这一特点提高了患者的依从性，并使在医疗资源有限的地区更易于施用。然而，像所有药物一样，sulfadoxine（磺胺嘧啶）也并非没有副作用。一些患者可能会出现过敏反应、皮疹或胃肠道不适。因此，医疗提供者在治疗期间密切监测患者至关重要。近年来，对于疟疾寄生虫耐药性菌株出现的担忧日益增加。这种耐药性可能会降低sulfadoxine（磺胺嘧啶）和其他抗疟药物的疗效，使控制疟疾疫情变得愈加困难。研究人员正在积极探索替代治疗和联合疗法，以克服这一问题。尽管面临这些挑战，sulfadoxine（磺胺嘧啶）仍然是抗击疟疾的重要工具。它在旨在减少疟疾发病率的公共卫生倡议中的作用不可低估。在许多国家，特别是在非洲，sulfadoxine（磺胺嘧啶）是简单疟疾的标准治疗方案的一部分。总之，sulfadoxine（磺胺嘧啶）是一种重要的抗生素，在治疗疟疾和其他细菌感染方面发挥了关键作用。它的有效性，加上其较长的半衰期，使其在许多临床环境中成为实用的选择。然而，耐药性的上升突显了持续研究和开发新治疗策略的必要性。理解sulfadoxine（磺胺嘧啶）在现代医学中的作用，对于医疗专业人员和患者来说都是至关重要的，因为它仍然是全球抗击传染病的重要武器。