isoniazid

简明释义

英[ˌaɪsəʊˈnaɪəzɪd]美[ˌaɪsoʊˈnaɪəzɪd]

n. 异烟肼（抗结核药）

英英释义

单词用法

同义词

反义词

例句

1.Objective: To study the electrochemical response of isoniazid at electrochemical pretreated glassy carbon electrode (PGCE).

目的：研究异烟肼在电化学预处理玻碳电极上的电化学响应。

2.Objective to establish a method to determine free hydrazine in isoniazid injection by difference spectrophotometry.

目的建立差示分光光度法测定异烟肼注射液中游离肼的方法。

3.At least isoniazid and rifampicin-resistant two drugs for the 16.26 percent ratio.

至少耐异烟肼和利福平两种药的比例为16.26%。

4.Those who are sick with TB need effective TB treatment, and those without TB should receive preventive therapy with the drug isoniazid.

患结核病的艾滋病毒携带者需要获得有效的结核治疗，未患结核病者应服用异烟肼进行预防。

5.The use of isoniazid as single drug treatment for BCG vaccine-induced lymphadenitis is recommended only in the Netherlands.

仅荷兰推荐使用异烟肼单药疗法治疗卡介苗诱发的淋巴腺炎。

6.OBJECTIVE: To study the general pattern and characteristics of adverse drug reactions caused by isoniazid .

目的：探讨异烟肼不良反应发生的特点和一般规律，为临床合理用药提供参考。

7.The drug isoniazid is widely used in the treatment of tuberculosis .

异烟肼是广泛用于治疗结核的药物。

8.OBJECTIVE To determine the compatibility stability of levofloxacin hydrochloride and sodium chloride injection with isoniazid injection.

目的考察盐酸左氧氟沙星氯化钠注射液与异烟肼注射液配伍稳定性。

9.Common side effects of isoniazid include nausea and fatigue.

异烟肼的常见副作用包括恶心和疲劳。

10.It is important to take isoniazid exactly as prescribed to avoid resistance.

按医嘱服用异烟肼非常重要，以避免耐药性。

11.The doctor prescribed isoniazid for the treatment of tuberculosis.

医生开了异烟肼用于治疗结核病。

12.Patients taking isoniazid should be monitored for liver function.

服用异烟肼的患者应监测肝功能。

13.Some patients may experience peripheral neuropathy while on isoniazid.

一些患者在服用异烟肼期间可能会出现周围神经病。

作文

Isoniazid, a medication primarily used to treat and prevent tuberculosis (TB), has played a crucial role in public health since its introduction in the 1950s. This drug is particularly effective against Mycobacterium tuberculosis, the bacteria responsible for TB. The mechanism of action of isoniazid involves inhibiting the synthesis of mycolic acids, which are essential components of the bacterial cell wall. By disrupting this process, isoniazid effectively kills the bacteria and helps the immune system to combat the infection.The use of isoniazid is not without its challenges. One of the most significant issues associated with this medication is the potential for side effects. Common side effects include liver toxicity, peripheral neuropathy, and allergic reactions. To mitigate these risks, healthcare providers often recommend vitamin B6 supplementation for patients taking isoniazid to help prevent nerve damage. It is important for patients to be monitored regularly while on this medication to ensure that any adverse effects are identified and managed promptly.In addition to its effectiveness, isoniazid also has implications for public health policy. The World Health Organization (WHO) recommends isoniazid as part of the standard treatment regimen for TB, especially in high-burden countries where the disease remains endemic. The availability of isoniazid has significantly contributed to the decline of TB incidence in many parts of the world. However, the emergence of drug-resistant strains of TB presents a growing challenge. Some strains have developed resistance to isoniazid, leading to more complex treatment regimens and increased healthcare costs.The importance of adherence to treatment cannot be overstated. Patients prescribed isoniazid must complete the full course of therapy to ensure the best possible outcomes. Non-compliance can lead to treatment failure and the development of drug-resistant TB, which poses a significant threat to both individual and public health. Education and support for patients are critical components of successful TB management, and healthcare providers play a vital role in promoting adherence to medication.Furthermore, research continues to explore new formulations and combinations of drugs that include isoniazid. For example, studies are examining fixed-dose combinations that simplify treatment regimens and improve patient compliance. Innovations in drug delivery systems are also being investigated to enhance the efficacy of isoniazid and reduce side effects.In conclusion, isoniazid remains a cornerstone in the fight against tuberculosis. Its ability to effectively treat and prevent TB has made it an invaluable tool in global health efforts. However, the challenges associated with its use highlight the need for ongoing research, patient education, and public health initiatives to ensure that this powerful medication continues to benefit those at risk of or suffering from TB. As we advance in our understanding of infectious diseases, the role of isoniazid will undoubtedly evolve, but its significance in the history of medicine is firmly established. Through continued vigilance and innovation, we can maintain the effectiveness of isoniazid and work towards a future where tuberculosis is no longer a global threat.

异烟肼，一种主要用于治疗和预防结核病（TB）的药物，自20世纪50年代引入以来，在公共卫生中发挥了至关重要的作用。这种药物对结核分枝杆菌，导致结核病的细菌，特别有效。isoniazid的作用机制涉及抑制分枝杆菌细胞壁的重要成分——脂肪酸的合成。通过破坏这一过程，isoniazid有效地杀死细菌并帮助免疫系统对抗感染。使用isoniazid并非没有挑战。与这种药物相关的最大问题之一是潜在的副作用。常见的副作用包括肝毒性、周围神经病和过敏反应。为了减轻这些风险，医疗提供者通常建议服用维生素B6补充剂，以帮助预防神经损伤。在服用这种药物期间，患者需要定期监测，以确保及时识别和管理任何不良反应。除了其有效性外，isoniazid还对公共卫生政策产生影响。世界卫生组织（WHO）建议将isoniazid作为结核病标准治疗方案的一部分，特别是在结核病仍然流行的高负担国家。isoniazid的可用性显著促进了许多地区结核病发病率的下降。然而，耐药性结核菌株的出现带来了日益严峻的挑战。一些菌株已对isoniazid产生耐药性，导致更复杂的治疗方案和增加的医疗费用。遵守治疗的重要性不容小觑。被处方isoniazid的患者必须完成整个治疗课程，以确保最佳的结果。不遵守可能导致治疗失败和耐药性结核病的发展，对个人和公共卫生构成重大威胁。教育和支持患者是成功管理结核病的关键组成部分，医疗提供者在促进药物遵从性方面发挥着至关重要的作用。此外，研究仍在继续探索包括isoniazid的新配方和药物组合。例如，研究正在审查固定剂量组合，以简化治疗方案并改善患者的依从性。药物递送系统的创新也在研究中，以增强isoniazid的疗效并减少副作用。总之，isoniazid仍然是抗击结核病的基石。其有效治疗和预防结核病的能力使其成为全球健康工作中的一项宝贵工具。然而，与其使用相关的挑战突显了持续研究、患者教育和公共卫生倡议的必要性，以确保这种强效药物继续惠及面临或患有结核病的人群。随着我们对传染病理解的不断深入，isoniazid的角色无疑会发展，但它在医学历史中的重要性是坚定不移的。通过持续的警惕和创新，我们可以保持isoniazid的有效性，并努力实现一个结核病不再是全球威胁的未来。