contact inhibitor

简明释义

隔离层

英英释义

例句

1.The study focused on how contact inhibitor 接触抑制 affects cell migration and tissue regeneration.

该研究集中于接触抑制 接触抑制如何影响细胞迁移和组织再生。

2.Cancer cells often lose their contact inhibitor 接触抑制 properties, allowing them to grow uncontrollably.

癌细胞通常失去它们的接触抑制 接触抑制特性，从而允许它们不受控制地生长。

3.In normal tissue, cells exhibit contact inhibitor 接触抑制 behavior to prevent overcrowding.

在正常组织中，细胞表现出接触抑制 接触抑制行为，以防止过度拥挤。

4.Understanding contact inhibitor 接触抑制 could lead to new therapies for preventing tumor growth.

理解接触抑制 接触抑制可能会导致新的治疗方法，以防止肿瘤生长。

5.Research shows that contact inhibitor 接触抑制 mechanisms can be restored in certain cancer treatments.

研究表明，在某些癌症治疗中可以恢复接触抑制 接触抑制机制。

作文

In the realm of cellular biology, the term contact inhibitor refers to a critical regulatory mechanism that controls cell growth and proliferation. This phenomenon is particularly important in maintaining tissue homeostasis and preventing uncontrolled cell division, which can lead to cancerous growths. When cells come into contact with one another, they receive signals that inhibit further growth and division. This process is essential for normal tissue development and repair, as it ensures that cells do not overcrowd and disrupt the functioning of tissues. 接触抑制是细胞生长和繁殖的重要调节机制，尤其在维持组织的稳态和防止细胞失控分裂方面具有重要意义。 The discovery of contact inhibitors has provided significant insights into cancer research. Cancer cells often lose the ability to respond to these inhibitory signals, allowing them to proliferate uncontrollably even when they are in close proximity to other cells. This loss of contact inhibition is one of the hallmarks of cancerous transformation. For instance, studies have shown that tumor cells can grow in dense cultures without exhibiting the normal growth arrest that healthy cells would experience. Understanding how contact inhibitors function at the molecular level could lead to novel therapeutic strategies aimed at restoring this crucial regulatory mechanism in cancer cells. Moreover, the role of contact inhibition extends beyond cancer biology. It is also involved in processes such as wound healing, where cells need to migrate and proliferate in a controlled manner to repair damaged tissues. During this process, cells initially divide to replace lost or damaged cells, but as they fill the wound area and begin to touch one another, contact inhibition kicks in, slowing down their proliferation. This balance between cell division and inhibition is vital for proper healing and regeneration. Research on contact inhibitors has also revealed their involvement in embryonic development. As embryos develop, cells must grow and differentiate while maintaining proper spatial organization. Contact inhibition helps regulate this process by ensuring that cells do not overpopulate certain areas, which could lead to developmental defects. For example, if cells fail to exhibit contact inhibition during early development, it may result in malformed organs or other serious congenital issues. In conclusion, the concept of contact inhibitors is fundamental to our understanding of cell biology, particularly in the context of cancer, tissue repair, and development. The mechanisms behind contact inhibition are complex and involve various signaling pathways and molecular interactions. Continued research in this area holds promise for advancing our knowledge of how to manipulate these processes for therapeutic benefit. By restoring contact inhibition in cancer cells, we may be able to develop more effective treatments that prevent tumor growth and improve patient outcomes. In summary, contact inhibitors play a pivotal role in regulating cell behavior, and understanding their function is crucial for both basic science and clinical applications.

在细胞生物学领域，术语接触抑制指的是一种关键的调节机制，用于控制细胞的生长和增殖。这种现象在维持组织稳态和防止细胞失控分裂方面尤为重要，这可能导致癌症的发生。当细胞相互接触时，它们会收到信号，抑制进一步的生长和分裂。这个过程对正常组织的发育和修复至关重要，因为它确保细胞不会过度拥挤，从而干扰组织的功能。接触抑制是细胞生长和繁殖的重要调节机制，尤其在维持组织的稳态和防止细胞失控分裂方面具有重要意义。对接触抑制的发现为癌症研究提供了重要的见解。癌细胞通常失去响应这些抑制信号的能力，使它们即使在与其他细胞紧密接触时也能失控增殖。这种对接触抑制的丧失是癌变的一个标志。例如，研究表明，肿瘤细胞可以在密集培养中生长，而不会表现出健康细胞所经历的正常生长停滞。理解接触抑制在分子水平上的功能可能会导致新的治疗策略，旨在恢复癌细胞中这一关键的调节机制。此外，接触抑制的作用不仅限于癌症生物学。它还参与伤口愈合等过程，在这些过程中，细胞需要以受控的方式迁移和增殖，以修复受损的组织。在这一过程中，细胞最初会分裂以替代失去或损坏的细胞，但随着它们填补伤口区域并开始彼此接触，接触抑制就会启动，减缓它们的增殖。这种细胞分裂和抑制之间的平衡对于适当的愈合和再生至关重要。关于接触抑制的研究还揭示了其在胚胎发育中的作用。随着胚胎的发展，细胞必须生长和分化，同时保持适当的空间组织。接触抑制通过确保细胞不会过度占据某些区域，从而调节这一过程，这可能导致发育缺陷。例如，如果细胞在早期发育过程中未能表现出接触抑制，可能会导致器官畸形或其他严重的先天性问题。总之，接触抑制的概念对于我们理解细胞生物学至关重要，特别是在癌症、组织修复和发育的背景下。接触抑制背后的机制复杂，涉及各种信号通路和分子相互作用。在这一领域的持续研究有望推进我们对如何操纵这些过程以获得治疗益处的认识。通过恢复癌细胞中的接触抑制，我们可能能够开发出更有效的治疗方法，防止肿瘤生长，改善患者的预后。总之，接触抑制在调节细胞行为方面发挥着关键作用，理解其功能对于基础科学和临床应用都至关重要。