bacillus calmette guerin

简明释义

结核预防注射

英英释义

例句

1.Healthcare professionals must be trained on the administration of bacillus calmette guerin (卡介苗) injections.

医疗专业人员必须接受关于bacillus calmette guerin（卡介苗）注射的培训。

2.Research shows that bacillus calmette guerin (卡介苗) can stimulate the immune system.

研究表明，bacillus calmette guerin（卡介苗）可以刺激免疫系统。

3.The vaccine for tuberculosis is derived from the bacillus calmette guerin (卡介苗).

结核病的疫苗是由bacillus calmette guerin（卡介苗）提取而来的。

4.Patients often receive the bacillus calmette guerin (卡介苗) as part of their treatment plan for bladder cancer.

患者通常在膀胱癌治疗方案中接受bacillus calmette guerin（卡介苗）。

5.The effectiveness of bacillus calmette guerin (卡介苗) in preventing tuberculosis has been well documented.

bacillus calmette guerin（卡介苗）在预防结核病方面的有效性已有充分的文献记录。

作文

The discovery of vaccines has been one of the most significant advancements in medical science. Among these, the vaccine derived from the bacterium known as bacillus calmette guerin (BCG) plays a crucial role in the prevention of tuberculosis. Developed in the early 20th century by Albert Calmette and Camille Guérin, this vaccine has saved countless lives worldwide. Understanding the history and application of bacillus calmette guerin is essential for appreciating its impact on global health.Tuberculosis (TB) is a contagious disease caused by the bacterium Mycobacterium tuberculosis, which primarily affects the lungs but can also impact other parts of the body. The need for an effective vaccine became apparent as TB was responsible for a significant number of deaths in the early 1900s. In response to this public health crisis, Calmette and Guérin began their work on a weakened strain of Mycobacterium bovis, which is closely related to M. tuberculosis. Their research culminated in the creation of the BCG vaccine, which was first used in humans in 1921.The mechanism of the bacillus calmette guerin vaccine involves stimulating the immune system to recognize and fight against the bacteria that cause tuberculosis. When administered, the vaccine introduces a live, attenuated strain of the bacterium into the body. This triggers an immune response, training the body’s defenses to respond more effectively should it encounter the actual TB bacteria in the future. The effectiveness of BCG varies across different populations and geographical regions, but it has been shown to provide significant protection against severe forms of TB in children.Over the decades, the use of bacillus calmette guerin has expanded beyond tuberculosis prevention. It has also been found to have applications in treating certain types of bladder cancer. Intravesical administration of BCG has become a standard treatment for superficial bladder tumors, showcasing the versatility of this vaccine beyond its original purpose. This dual functionality underscores the importance of continued research and innovation in the field of immunology.Despite its benefits, the bacillus calmette guerin vaccine is not without limitations. Its efficacy in preventing pulmonary TB in adults is variable, and there are concerns regarding the waning immunity over time. Additionally, the vaccine does not provide complete protection against TB, leading to ongoing efforts to develop more effective vaccines. Researchers are exploring novel approaches, including recombinant vaccines and adjuvants, to enhance the immune response and improve overall protection against tuberculosis.In conclusion, the bacillus calmette guerin vaccine represents a remarkable achievement in the fight against tuberculosis and continues to be a vital tool in public health. Its historical significance, coupled with its evolving applications in medicine, highlights the importance of vaccines in controlling infectious diseases. As we advance our understanding of immunology and vaccine development, it is crucial to build upon the legacy of BCG to ensure a healthier future for all. The journey of bacillus calmette guerin from a laboratory experiment to a global health intervention exemplifies the power of scientific inquiry and the relentless pursuit of knowledge in the quest to combat disease.

疫苗的发现是医学科学中最重要的进展之一。在这些疫苗中，源于一种细菌的疫苗被称为卡介苗（BCG）在预防结核病方面发挥着至关重要的作用。由阿尔贝·卡尔梅特和卡米尔·盖兰在20世纪初开发，这种疫苗拯救了全球无数生命。理解卡介苗的历史和应用对于欣赏其对全球健康的影响至关重要。结核病（TB）是一种由结核分枝杆菌引起的传染病，主要影响肺部，但也可以影响身体的其他部分。随着结核病在20世纪初造成了大量死亡，迫切需要有效的疫苗。为了应对这一公共卫生危机，卡尔梅特和盖兰开始研究一种减毒的牛型结核杆菌株，该菌株与M. tuberculosis密切相关。他们的研究最终导致了BCG疫苗的创建，该疫苗于1921年首次用于人类。卡介苗疫苗的机制涉及刺激免疫系统识别和抵抗导致结核病的细菌。当施用时，疫苗将一种活的减毒菌株引入体内。这触发了免疫反应，训练身体的防御系统在未来遇到真正的结核病菌时做出更有效的反应。BCG的有效性在不同的人群和地理区域中有所不同，但已被证明能显著保护儿童免受严重形式的结核病。几十年来，卡介苗的使用超出了结核病预防的范围。它还被发现可以用于治疗某些类型的膀胱癌。BCG的膀胱内给药已成为治疗表浅膀胱肿瘤的标准疗法，展示了这种疫苗在其原始目的之外的多功能性。这种双重功能强调了在免疫学领域继续研究和创新的重要性。尽管有其好处，卡介苗疫苗并非没有局限性。它在预防成人肺结核方面的有效性是可变的，并且对免疫力随着时间的推移减弱的担忧。此外，该疫苗并未提供对结核病的完全保护，导致对开发更有效疫苗的持续努力。研究人员正在探索新颖的方法，包括重组疫苗和佐剂，以增强免疫反应并改善对结核病的整体保护。总之，卡介苗疫苗代表了在抗击结核病斗争中的一项显著成就，并继续作为公共卫生中的重要工具。其历史意义，以及在医学中不断发展的应用，突显了疫苗在控制传染病中的重要性。随着我们对免疫学和疫苗开发的理解的深入，建立在BCG遗产之上的基础对于确保所有人的健康未来至关重要。卡介苗从实验室实验到全球健康干预的旅程充分体现了科学探究的力量，以及在与疾病作斗争的追求中对知识的不懈追求。