active zone

简明释义

活性区

英英释义

例句

1.The active zone in the software application allows users to interact with the interface.

软件应用中的活跃区域允许用户与界面进行交互。

2.In the game, players must stay within the active zone to earn points.

在游戏中，玩家必须待在活跃区域内才能得分。

3.The active zone in a neuron is where neurotransmitters are released.

神经元中的活跃区域是神经递质释放的地方。

4.The research focused on the active zone of the synapse for understanding signal transmission.

这项研究集中在突触的活跃区域上，以理解信号传递。

5.During the event, the active zone will be marked with bright banners.

在活动期间，活跃区域将用明亮的横幅标记。

作文

In the realm of neuroscience, the term active zone refers to a specialized area at the presynaptic membrane where neurotransmitter release occurs. This region is crucial for synaptic transmission, as it is where vesicles containing neurotransmitters are docked and released into the synaptic cleft. Understanding the function of the active zone is essential for comprehending how signals are transmitted between neurons and how communication in the nervous system operates at a fundamental level.The active zone is characterized by a high density of proteins that play vital roles in the process of exocytosis, which is the mechanism through which neurotransmitters are released. These proteins include calcium channels, which open in response to an influx of calcium ions, triggering the fusion of synaptic vesicles with the presynaptic membrane. The precise arrangement of these proteins within the active zone ensures that neurotransmitter release is both rapid and efficient, allowing for effective communication between neurons.Research has shown that the structure and function of the active zone can vary significantly between different types of neurons and even within the same neuron under varying conditions. For instance, during periods of high neuronal activity, the active zone may adapt to facilitate increased neurotransmitter release, demonstrating the plasticity of synaptic connections. This adaptability is crucial for processes such as learning and memory, where the strength of synaptic connections must be modified to encode new information.Furthermore, abnormalities in the structure or function of the active zone have been implicated in various neurological disorders. Conditions such as epilepsy, schizophrenia, and autism spectrum disorders have been linked to disruptions in synaptic transmission, highlighting the importance of the active zone in maintaining healthy brain function. Understanding these mechanisms may pave the way for developing targeted therapies aimed at restoring normal synaptic function in affected individuals.In summary, the active zone is a critical component of synaptic transmission, serving as the site for neurotransmitter release and facilitating communication between neurons. Its intricate structure and dynamic nature are essential for the proper functioning of the nervous system. Continued research into the active zone will not only enhance our understanding of basic neural processes but may also lead to significant advancements in treating neurological disorders that arise from synaptic dysfunctions.

在神经科学领域，术语active zone指的是突触前膜上的一个专门区域，在该区域内神经递质的释放发生。这个区域对突触传递至关重要，因为它是包含神经递质的囊泡停靠并释放到突触间隙的地方。理解active zone的功能对于理解信号如何在神经元之间传递以及神经系统如何在基础层面上运作至关重要。active zone的特点是高密度的蛋白质，这些蛋白质在胞吐过程中发挥着重要作用，胞吐是神经递质释放的机制。这些蛋白质包括钙通道，它们在钙离子流入后打开，触发突触囊泡与突触前膜的融合。这些蛋白质在active zone内的精确排列确保了神经递质释放既快速又高效，从而允许神经元之间有效的沟通。研究表明，active zone的结构和功能在不同类型的神经元之间甚至在同一神经元的不同条件下可能会显著变化。例如，在神经活动高峰期间，active zone可能会适应以促进神经递质的增加释放，这表明突触连接的可塑性。这种适应性对于学习和记忆等过程至关重要，在这些过程中，突触连接的强度必须被修改以编码新信息。此外，active zone的结构或功能异常与各种神经系统疾病有关。癫痫、精神分裂症和自闭症谱系障碍等疾病与突触传递的干扰有关，这突显了active zone在维持健康大脑功能中的重要性。理解这些机制可能为开发针对性的治疗方案铺平道路，旨在恢复受影响个体的正常突触功能。总之，active zone是突触传递的关键组成部分，作为神经递质释放的场所，促进神经元之间的沟通。其复杂的结构和动态特性对神经系统的正常功能至关重要。对active zone的持续研究不仅将增强我们对基本神经过程的理解，还可能在治疗因突触功能障碍而引起的神经系统疾病方面取得重大进展。