muscarine

简明释义

英[ˈmʌskəriːn;ˈmʌskərɪn]美[ˈmʌskəˌriːn]

n. 毒蝇碱；[有化] 蕈毒碱；腐鱼毒

英英释义

单词用法

同义词

反义词

例句

1.Their work determined that muscarine stimulated neural activity, leading to locomotion in the laboratory lampreys.

他们发现毒蕈碱能刺激神经兴奋，并引起八目鳗运动。

2.Symptoms associated with Parkinson's can be helped by reducing acetylcholine-mediated neurotransmission in the brain, but little work has focused on brainstem muscarine receptors in this disease.

帕金森病的这些症状可以通过减少脑内乙酰胆碱介导的神经传递而缓解，但很少有人注意到脑干细胞毒蕈碱受体的作用。

3.BACKGROUND: Muscarine receptor plays a key role in adjusting contraction of detrusor muscle cell, and M3R, isoforms of its receptor, can mediate contraction of detrusor muscle cell directly.

背景：毒蕈碱受体在调节逼尿肌细胞收缩过程中起重要作用，其受体亚型M3R直接介导逼尿肌细胞收缩。

4.Symptoms associated with Parkinson's can be helped by reducing acetylcholine-mediated neurotransmission in the brain, but little work has focused on brainstem muscarine receptors in this disease.

帕金森病的这些症状可以通过减少脑内乙酰胆碱介导的神经传递而缓解，但很少有人注意到脑干细胞毒蕈碱受体的作用。

5.In high doses, muscarine can cause excessive salivation and sweating.

在高剂量下，muscarine可能导致过度流涎和出汗。

6.Doctors may use muscarine as a reference when discussing cholinergic drugs.

医生在讨论胆碱能药物时可能会以muscarine作为参考。

7.Researchers are studying how muscarine interacts with neurotransmitters.

研究人员正在研究muscarine如何与神经递质相互作用。

8.The presence of muscarine in certain mushrooms can be toxic to humans.

某些蘑菇中存在的muscarine对人类可能是有毒的。

9.The effects of muscarine on the heart can lead to a decrease in heart rate.

对心脏的muscarine影响可能导致心率下降。

作文

Muscarine is a fascinating compound that plays a significant role in the field of pharmacology and neuroscience. It is an alkaloid derived from the mushroom Amanita muscaria, commonly known as the fly agaric. This compound has garnered attention due to its potent effects on the nervous system, particularly its ability to mimic the action of the neurotransmitter acetylcholine. In this essay, we will explore the properties of muscarine and its implications in both scientific research and potential medicinal applications.To understand muscarine, one must first recognize its relationship with the cholinergic system. This system is crucial for various bodily functions, including muscle movement, memory, and learning. When muscarine binds to muscarinic receptors in the brain, it can lead to a range of physiological effects. These effects can include increased salivation, sweating, and even changes in heart rate. Such interactions highlight the importance of muscarine in understanding how neurotransmitters function and how they can be influenced by external compounds.Moreover, the study of muscarine has implications beyond basic science. Researchers have investigated its potential therapeutic uses, particularly in treating conditions related to the cholinergic system. For instance, there is ongoing research into the role of muscarine in Alzheimer's disease, where acetylcholine levels are often depleted. By studying how muscarine interacts with receptors, scientists hope to develop drugs that can enhance cognitive function in affected individuals.Despite its potential benefits, muscarine also poses risks. High doses can lead to toxicity, resulting in symptoms such as nausea, vomiting, and respiratory distress. This dual nature of muscarine underscores the importance of careful dosage and administration in any potential therapeutic context. As researchers continue to explore its properties, they must balance the benefits against the risks to ensure safety in medical applications.In addition to its medicinal implications, muscarine serves as a prime example of how natural compounds can influence our understanding of biological processes. The study of such substances not only enriches our knowledge of pharmacology but also encourages further exploration of other natural products that may offer similar insights or benefits. By examining the effects of muscarine, scientists can gain a better understanding of the complexities of neurotransmission and receptor interactions.In conclusion, muscarine is a remarkable compound that exemplifies the intersection of nature and science. Its ability to mimic acetylcholine and interact with the cholinergic system provides valuable insights into neurological functions and potential treatments for various disorders. While the risks associated with muscarine cannot be overlooked, its study continues to inspire research aimed at harnessing its properties for therapeutic use. As we delve deeper into the world of natural compounds, muscarine stands out as a key player in the quest for understanding and improving human health.

muscarine 是一种引人入胜的化合物，在药理学和神经科学领域发挥着重要作用。它是一种源自蘑菇 Amanita muscaria 的生物碱，通常被称为苍蝇毒伞。这种化合物因其对神经系统的强效作用而受到关注，尤其是它模仿神经递质乙酰胆碱的作用。在本文中，我们将探讨 muscarine 的特性及其在科学研究和潜在医学应用中的意义。要理解 muscarine，首先必须认识到它与胆碱能系统的关系。该系统对各种身体功能至关重要，包括肌肉运动、记忆和学习。当 muscarine 与大脑中的毒蕈碱受体结合时，会导致一系列生理效应。这些效应可能包括唾液分泌增加、出汗，甚至心率变化。这种相互作用突显了 muscarine 在理解神经递质如何发挥作用以及如何受到外部化合物影响方面的重要性。此外，对 muscarine 的研究超越了基础科学。研究人员正在调查其潜在的治疗用途，特别是在治疗与胆碱能系统相关的疾病方面。例如，目前正在研究 muscarine 在阿尔茨海默病中的作用，在这种情况下，乙酰胆碱水平通常会降低。通过研究 muscarine 如何与受体相互作用，科学家希望开发出能增强受影响个体认知功能的药物。尽管有潜在的好处，但 muscarine 也存在风险。高剂量可能导致毒性，出现恶心、呕吐和呼吸窘迫等症状。这种 muscarine 的双重性质强调了在任何潜在治疗背景下仔细剂量和管理的重要性。随着研究人员继续探索其特性，他们必须在确保医疗应用安全的同时平衡益处与风险。除了其医学意义，muscarine 还作为自然化合物如何影响我们对生物过程理解的典范。对这些物质的研究不仅丰富了我们对药理学的认识，还鼓励进一步探索其他可能提供类似见解或益处的天然产品。通过检查 muscarine 的影响，科学家可以更好地理解神经传导和受体相互作用的复杂性。总之，muscarine 是一种非凡的化合物，体现了自然与科学的交汇。它模仿乙酰胆碱并与胆碱能系统相互作用的能力为神经功能和各种疾病的潜在治疗提供了宝贵的见解。虽然与 muscarine 相关的风险不容忽视，但对其研究仍然激励着旨在利用其特性进行治疗使用的研究。随着我们深入探索天然化合物的世界，muscarine 作为理解和改善人类健康的关键角色脱颖而出。