distribution coefficient

简明释义

分布系数

英英释义

例句

1.A higher distribution coefficient indicates that a substance is more soluble in organic solvents than in water.

更高的 分配系数 表明某种物质在有机溶剂中的溶解度高于水中。

2.Scientists often use the distribution coefficient to assess the bioavailability of nutrients.

科学家们常用 分配系数 来评估营养素的生物利用度。

3.The distribution coefficient can vary significantly between different chemical compounds.

不同化合物之间的 分配系数 可能会有显著差异。

4.In environmental studies, the distribution coefficient helps predict the movement of pollutants.

在环境研究中，分配系数 有助于预测污染物的运动。

5.The distribution coefficient is crucial in determining how a drug will behave in the body.

分配系数 对于确定药物在体内的行为至关重要。

作文

The concept of the distribution coefficient is fundamental in various fields, including chemistry, environmental science, and pharmacology. The distribution coefficient is defined as the ratio of the concentration of a compound in one solvent to its concentration in another solvent at equilibrium. This parameter is crucial for understanding how substances partition between different phases, which can significantly affect their behavior and effectiveness in various applications.In chemistry, the distribution coefficient helps predict how a solute will distribute itself between two immiscible liquids, such as oil and water. For instance, when studying the solubility of a drug in the human body, scientists often look at the distribution coefficient to determine how well the drug will be absorbed and where it will concentrate. A high distribution coefficient indicates that the compound prefers the organic phase (often lipid-soluble), while a low coefficient suggests a preference for the aqueous phase (water-soluble). This information is vital for formulating effective pharmaceuticals and ensuring optimal therapeutic outcomes.Moreover, in environmental science, the distribution coefficient plays a critical role in assessing the fate of pollutants in the environment. It helps researchers understand how contaminants move through soil and water systems. For example, a pollutant with a high distribution coefficient may tend to accumulate in sediments or biota, posing risks to ecosystems and human health. By analyzing the distribution coefficient, scientists can predict the long-term behavior of these substances and develop strategies to mitigate their impact.Pharmacologists also rely heavily on the distribution coefficient when designing new drugs. The ability of a drug to cross cell membranes and reach its target site is influenced by its distribution coefficient. Drugs that exhibit favorable distribution properties are more likely to be effective and have fewer side effects. Therefore, understanding and optimizing the distribution coefficient is essential in drug development processes.In conclusion, the distribution coefficient is a vital parameter that influences various scientific disciplines. Its significance lies in its ability to provide insights into how compounds behave in different environments, whether in the human body or the natural world. Whether it is for developing new medications, assessing environmental risks, or conducting chemical research, mastering the concept of the distribution coefficient is crucial for professionals in these fields. As we continue to advance our understanding of this important metric, we can better predict and manipulate the behavior of substances, leading to improved outcomes in health, safety, and environmental protection.

分配系数的概念在化学、环境科学和药理学等多个领域中都是基础性的。分配系数被定义为一种化合物在一种溶剂中的浓度与其在另一种溶剂中的浓度之比，在平衡状态下。这一参数对于理解物质在不同相之间的分配至关重要，这可能显著影响它们在各种应用中的行为和有效性。在化学中，分配系数有助于预测溶质将在两种不混溶的液体（如油和水）之间如何分布。例如，在研究药物在人体中的溶解度时，科学家经常查看分配系数，以确定药物的吸收效果及其集中位置。高分配系数表示化合物更倾向于有机相（通常是脂溶性），而低系数则表明其更偏好于水相（水溶性）。这些信息对于制定有效的药物配方和确保最佳治疗结果至关重要。此外，在环境科学中，分配系数在评估污染物在环境中的命运方面也发挥着关键作用。它帮助研究人员理解污染物在土壤和水系统中的移动。例如，具有高分配系数的污染物可能倾向于在沉积物或生物体内积累，从而对生态系统和人类健康构成风险。通过分析分配系数，科学家可以预测这些物质的长期行为，并制定减轻其影响的策略。药理学家在设计新药时也非常依赖分配系数。药物跨越细胞膜并到达目标部位的能力受到其分配系数的影响。表现出有利分配特性的药物更有可能有效且副作用较少。因此，理解和优化分配系数在药物开发过程中至关重要。总之，分配系数是影响多个科学学科的重要参数。它的重要性在于能够提供关于化合物在不同环境中行为的见解，无论是在人体内还是自然界中。无论是开发新药、评估环境风险，还是进行化学研究，掌握分配系数的概念对于这些领域的专业人士来说都是至关重要的。随着我们继续加深对这一重要指标的理解，我们可以更好地预测和操控物质的行为，从而在健康、安全和环境保护方面取得更好的结果。