allotype

简明释义

[ˈæləˌtaɪp][ˈæləˌtaɪp]

n. 同种抗免疫球蛋白

英英释义

An allotype is a variant form of an antibody that is distinguished by the presence of specific genetic markers, which can be used to identify different alleles within a population.

allotype 是抗体的一种变体形式,通过特定的遗传标记来区分,这些标记可用于识别群体中的不同等位基因。

单词用法

allotype variation

同种异型变异

igg allotype

IgG同种异型

determine allotype

确定同种异型

analyze allotype

分析同种异型

同义词

isoform

同种异构体

Isoforms are different forms of the same protein that may have slightly different functions.

同种异构体是同一种蛋白质的不同形式,可能具有略微不同的功能。

variant

变体

Genetic variants can influence an individual's susceptibility to diseases.

遗传变体可以影响个体对疾病的易感性。

allele

等位基因

Alleles are different versions of a gene that can result in varying traits.

等位基因是基因的不同版本,可能导致不同的性状。

反义词

homozygote

纯合子

A homozygote has two identical alleles for a particular gene.

纯合子在特定基因上有两个相同的等位基因。

isotype

同种型

Isotypes are used to refer to different classes of antibodies.

同种型用于指不同类别的抗体。

例句

1.We can also adopt sand shell moulding or metal mold casting as for allotype castings.

对异形铸件,还可用砂型铸造或金属型铸造。

2.We can also adopt sand shell moulding or metal mold casting as for allotype castings.

对异形铸件,还可用砂型铸造或金属型铸造。

3.The study focused on the variations of the immune response related to different allotypes.

该研究集中在与不同全型相关的免疫反应变异上。

4.Researchers discovered that certain allotypes can influence susceptibility to diseases.

研究人员发现某些全型可能会影响对疾病的易感性。

5.The presence of different allotypes in a population can indicate evolutionary adaptations.

种群中不同的全型的存在可以表明进化适应。

6.In genetic studies, identifying allotypes helps in understanding population diversity.

在遗传研究中,识别全型有助于理解种群多样性。

7.The allotype of an antibody can affect its binding affinity to antigens.

抗体的全型会影响其与抗原的结合亲和力。

作文

In the fascinating world of immunology, the term allotype refers to the genetic variations of antibodies that are present within a species. These variations can influence an individual's immune response and are crucial for understanding how different people may react to infections or vaccines. The concept of allotype is particularly important in the study of monoclonal antibodies, which are laboratory-made molecules that can mimic the immune system's ability to fight off harmful pathogens. When we delve deeper into the significance of allotype, we discover that it plays a pivotal role in the field of personalized medicine. Each person has a unique set of antibodies that can be classified based on their allotype. This uniqueness means that treatments, especially those involving immunotherapy, can be tailored to suit individual patients more effectively. For instance, knowing a patient's allotype can help healthcare providers predict how well a patient might respond to a particular treatment or vaccine. Moreover, the study of allotype extends beyond individual health. It also has implications for population health and epidemiology. Researchers can track the distribution of different allotypes in various populations, helping them understand how genetic diversity influences disease prevalence and susceptibility. For example, certain allotypes may offer better protection against specific viruses or bacteria, while others may leave individuals more vulnerable. This knowledge can inform public health strategies and vaccination campaigns, ensuring that they are effective across diverse populations. In addition to its applications in medicine, the concept of allotype enriches our understanding of evolutionary biology. By studying the variations in allotypes among different species, scientists can gain insights into how immune systems have evolved over time. This research can reveal patterns of adaptation and survival, shedding light on the complex interplay between organisms and their environments. Furthermore, the importance of allotype is exemplified in the context of organ transplantation. When a donor organ is transplanted into a recipient, the recipient's immune system may recognize the organ as foreign due to differences in allotype. This recognition can lead to rejection of the transplanted organ. Therefore, understanding the allotype of both the donor and the recipient is crucial for improving transplant outcomes and minimizing the risk of rejection. In conclusion, the term allotype encapsulates a vital aspect of immunology that has far-reaching implications in medicine, public health, and evolutionary biology. As research continues to evolve, the understanding of allotype will undoubtedly lead to more personalized and effective treatments, ultimately enhancing our ability to combat diseases and improve health outcomes for individuals and populations alike. Embracing the complexity of allotype variations will pave the way for innovative approaches in healthcare, making it a cornerstone of modern immunological studies.

在免疫学的迷人世界中,术语allotype指的是在一个物种内存在的抗体的遗传变异。这些变异可以影响个体的免疫反应,对于理解不同人可能如何对感染或疫苗产生反应至关重要。allotype的概念在单克隆抗体的研究中尤为重要,单克隆抗体是实验室制造的分子,可以模拟免疫系统抵御有害病原体的能力。当我们深入探讨allotype的重要性时,我们会发现它在个性化医学领域中发挥着关键作用。每个人都有一套独特的抗体,这些抗体可以根据其allotype进行分类。这种独特性意味着治疗,尤其是涉及免疫治疗的治疗,可以更有效地量身定制以适应个体患者。例如,了解患者的allotype可以帮助医疗提供者预测患者对特定治疗或疫苗的反应效果。此外,allotype的研究超越了个体健康。它还对群体健康和流行病学产生影响。研究人员可以追踪不同人群中不同allotypes的分布,帮助他们理解遗传多样性如何影响疾病的流行程度和易感性。例如,某些allotypes可能提供对特定病毒或细菌的更好保护,而其他则可能使个体更脆弱。这些知识可以为公共卫生战略和疫苗接种活动提供信息,确保它们在多样化人群中有效。除了在医学中的应用外,allotype的概念丰富了我们对进化生物学的理解。通过研究不同物种之间的allotypes的变异,科学家可以获得关于免疫系统如何随时间演变的见解。这项研究可以揭示适应和生存的模式,阐明生物体与其环境之间复杂的相互作用。此外,allotype的重要性在器官移植的背景下得到了体现。当一个供体器官被移植到受体中时,受体的免疫系统可能会由于allotype的差异而将该器官视为外来物。这种识别可能导致移植器官的排斥。因此,了解供体和受体的allotype对于改善移植结果和最小化排斥风险至关重要。总之,术语allotype概括了免疫学的一个重要方面,这在医学、公共卫生和进化生物学方面具有深远的影响。随着研究的不断发展,对allotype的理解无疑将导致更个性化和有效的治疗,从而最终增强我们对抗疾病和改善个体及人群健康结果的能力。接受allotype变异的复杂性将为医疗保健中的创新方法铺平道路,使其成为现代免疫学研究的基石。