absorption distribution

简明释义

吸收分布

英英释义

例句

1.The absorption distribution of light in different materials is crucial for designing optical devices.

不同材料中光的吸收分布对光学设备的设计至关重要。

2.The study focused on the absorption distribution of nutrients in the human body.

这项研究集中在营养素在人体内的吸收分布。

3.Pharmaceutical companies often analyze the absorption distribution of drugs to optimize their effectiveness.

制药公司通常分析药物的吸收分布以优化其效果。

4.Researchers measured the absorption distribution of pollutants in the water supply.

研究人员测量了水供应中的污染物的吸收分布。

5.Understanding the absorption distribution in soil can help improve agricultural practices.

了解土壤中的吸收分布可以帮助改善农业实践。

作文

In the realm of pharmacology, understanding the processes by which drugs are absorbed and distributed in the body is crucial for effective treatment outcomes. This is where the concept of absorption distribution (吸收分布) comes into play. The term refers to two key phases in the pharmacokinetics of a drug: how it enters the bloodstream and how it is dispersed throughout the body's tissues. Firstly, let's explore the absorption phase. When a drug is administered, whether orally, intravenously, or through other means, it must be absorbed into the bloodstream to exert its effects. Various factors influence this process, including the drug's formulation, the route of administration, and the physiological conditions of the patient. For instance, oral medications must pass through the gastrointestinal tract, where they can be affected by food intake, pH levels, and the presence of other substances. Once the drug is absorbed, the next phase is distribution. This involves the movement of the drug from the bloodstream into various tissues and organs. The extent and rate of distribution depend on several factors, such as blood flow to different areas of the body, the drug's solubility, and its ability to cross cell membranes. For example, lipophilic (fat-soluble) drugs tend to accumulate in fatty tissues, while hydrophilic (water-soluble) drugs may remain in the bloodstream or distribute more evenly across body fluids. The relationship between absorption distribution (吸收分布) is critical for determining the drug's efficacy and safety. If a drug is not adequately absorbed, it may not reach therapeutic levels in the bloodstream, rendering it ineffective. Conversely, if a drug is distributed too widely or accumulates in certain tissues, it could lead to toxicity or adverse effects. Therefore, understanding these processes helps healthcare professionals make informed decisions about dosing, timing, and routes of administration. Moreover, individual patient factors, such as age, weight, genetics, and existing health conditions, can significantly impact both absorption and distribution. For instance, elderly patients may have altered gastric pH and slower gastric emptying, affecting how quickly a drug is absorbed. Similarly, individuals with liver or kidney impairment may experience changes in drug metabolism and excretion, influencing the overall distribution of the drug within their bodies. In recent years, advancements in technology and research have provided deeper insights into the dynamics of absorption distribution (吸收分布). Techniques such as computer modeling, in vitro studies, and clinical trials have enhanced our understanding of how drugs behave in the body. This knowledge is essential for developing new medications and optimizing existing ones, ensuring that patients receive the most effective treatments possible. In conclusion, the concept of absorption distribution (吸收分布) is fundamental in pharmacology, influencing how drugs are absorbed into the bloodstream and distributed throughout the body. By comprehensively understanding these processes, healthcare professionals can better tailor treatments to meet individual patient needs, ultimately improving therapeutic outcomes. As research continues to evolve, so too will our understanding of these critical pharmacokinetic principles, paving the way for more effective and safer medications in the future.

在药理学领域，理解药物在体内的吸收和分布过程对于有效的治疗结果至关重要。这就是吸收分布（absorption distribution）这一概念发挥作用的地方。该术语指的是药物药代动力学中的两个关键阶段：药物如何进入血液以及如何在身体组织中分散。首先，让我们探讨吸收阶段。当药物被给药时，无论是口服、静脉注射还是通过其他方式，它必须被吸收到血液中才能发挥作用。各种因素影响这一过程，包括药物的配方、给药途径和患者的生理条件。例如，口服药物必须通过胃肠道，在此过程中可能受到食物摄入、pH值和其他物质存在的影响。一旦药物被吸收，接下来的阶段是分布。这涉及药物从血液中转移到各种组织和器官。分布的程度和速度取决于多个因素，例如血液流向身体不同区域的速度、药物的溶解性及其穿过细胞膜的能力。例如，脂溶性（脂溶性）的药物往往会在脂肪组织中积累，而水溶性药物则可能留在血液中或在体液中更均匀地分布。吸收分布（absorption distribution）之间的关系对于确定药物的疗效和安全性至关重要。如果药物没有充分吸收，它可能无法在血液中达到治疗水平，从而使其无效。相反，如果药物分布过广或在某些组织中积累，可能会导致毒性或不良反应。因此，了解这些过程有助于医疗专业人员就剂量、时间和给药途径做出明智的决定。此外，个体患者的因素，如年龄、体重、遗传和现有健康状况，可能会显著影响吸收和分布。例如，老年患者可能具有改变的胃酸度和较慢的胃排空，这会影响药物的吸收速度。同样，肝脏或肾脏功能受损的个体可能会经历药物代谢和排泄的变化，从而影响药物在其体内的整体分布。近年来，技术和研究的进步为我们提供了对吸收分布（absorption distribution）动态的更深入见解。计算机建模、体外研究和临床试验等技术增强了我们对药物在体内行为的理解。这种知识对于开发新药物和优化现有药物至关重要，确保患者获得尽可能有效的治疗。总之，吸收分布（absorption distribution）这一概念在药理学中是基础性的，影响药物如何被吸收到血液中以及如何在体内分布。通过全面理解这些过程，医疗专业人员可以更好地根据个体患者的需求量身定制治疗方案，从而改善治疗结果。随着研究的不断发展，我们对这些关键药代动力学原理的理解也将不断深化，为未来更有效和更安全的药物铺平道路。